Table 1 Patients’ characteristics at ICU admission
All (n = 507) | No VAP (n = 181) | VAP without lung abscess (n = 303) | VAP with lung abscess (n = 23) | P value | |
|---|---|---|---|---|---|
Male, n (%) | 368 (73) | 125 (69) | 224 (74) | 19 (83) | 0.277 |
Age, years ( mean ± SD) | 62 ± 12 | 62 ± 12 | 62 ± 12 | 55 ± 14 | 0.028 |
SAPS 2 (median, IQR) | 40 (32–48) | 40 (31–50) | 41 (34–49) | 42 (34–53) | 0.519 |
SOFA (median, IQR) | 5 (3–8) | 5 (3–8) | 5 (3–8) | 8 (4–9) | 0.071 |
Hypertension, n (%) | 243 (48) | 88 (48) | 143 (47) | 12 (52) | 0.875 |
Diabetes mellitus, n (%) | 162 (32) | 55 (30) | 99 (33) | 8 (35) | 0.835 |
Obesity, n (%) | 201 (40) | 74 (41) | 118 (39) | 9 (39) | 0.914 |
Smoker, n (%) | 122 (24) | 51 (28) | 70 (23) | 1 (4) | 0.035 |
Chronic heart disease, n (%) | 92 (18) | 35 (19) | 55 (18) | 2 (9) | 0.456 |
Chronic respiratory insufficiency, n (%) | 70 (14) | 21 (11) | 47 (16) | 2 (9) | 0.371 |
Chronic renal failure, n (%) | 42 (8) | 14 (8) | 27 (9) | 1 (4) | 0.706 |
Cancer, n (%) | 50 (10) | 16 (9) | 31 (10) | 3 (13) | 0.771 |
Immunocompromised status, n (%) | 60 (12) | 18 (10) | 39 (13) | 3 (13) | 0.618 |
Time from hospital to ICU admission, days (median, IQR) | 1 (0–3) | 1 (0–4) | 1 (0–2) | 2 (0–4) | 0.160 |
Probabilistic antibiotic therapy, n (%) | 319 (63) | 129 (71) | 173 (57) | 17 (74) | 0.004 |
Confirmed bacterial coinfection on admission, n (%) | 56 (11) | 13 (7) | 38 (13) | 5 (22) | 0.047 |
Dexamethasone use, n (%) | 429 (84) | 148 (82) | 259 (85) | 21 (91) | 0.325 |