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Table 1 Clinical characteristics of the study cohort

From: Therapeutic S100A8/A9 blockade inhibits myocardial and systemic inflammation and mitigates sepsis-induced myocardial dysfunction

Demographics

Total (62)

No left ventricular dysfunction (27)

Left ventricular dysfunction (35)

P-value

Age

72 (59–76)

65 (56–75)

73 (62–76)

0.119

Sex, male n (%)

30 (48.2)

13 (48.15)

17 (48.6)

0.974

SAPS

64 (56–75)

59 (52–69)

66 (58–76)

0.029

SOFA

9 (7–12)

9 (5–11)

10 (8–13)

0.047

Clinical frailty scale

3 (2–4)

2 (2–4)

3 (2–4)

0.241

Coronary artery disease, n (%)

9 (14.5)

3 (11.1)

6 (17.1)

0.504

Heart failure, n (%)

9 (14.5)

2 (7.4)

7 (20.0)

0.163

Diabetes mellitus, n (%)

10 (16.1)

4 (14.8)

6 (17.1)

0.805

Stroke or TIA, n (%)

10 (16.1)

3 (11.1)

7 (20.0)

0.345

Hypertension, n (%)

43 (69.4)

15 (55.6)

28 (80.0)

0.038

S100A8/A9 (µg/mL)

14.3 (6.9–32.1)

7.4 (4.5–22.9)

20.1 (11.8–36.1)

0.009

  1. The values are presented as median (IQR) or percentages. Statistical testing for continuous variables was performed with the Mann–Whitney U test, and for categorical variables with the Chi-squared test. SAPS, Simplified Acute Physiology Score; SOFA, Sequential Organ Failure Assessment; TIA, Transient ischemic attack