Table 2 Comparison of characteristics of platelet transfusion with and without suboptimal response based on a CCI < 7

Clinical and biological features before transfusion

Heart rate (/min)

104 (90–119)

106 (93–120)

98 (85–110)

0.0001

Heart rate > 100/min

282 (59.7%)

224 (64.2%)

58 (47.2%)

0.0009

Temperature, °C^a

37.0 (36.4–37.7)

37.1 (36.5–37.7)

36.9 (36.3–37.5)

0.0527

Temperature > 39°C^a

20 (4.4%)

18 (5.3%)

2 (1.7%)

0.0920

Mean arterial BP, mmHg

76.0 (69–88)

76 (69–88)

77 (71–85)

0.8933

Therapeutic anticoagulation

50 (10.6%)

28 (8.0%)

22 (17.9%)

0.0022

AKI requiring RRT

97 (20.6%)

64 (18.3%)

33 (26.8%)

0.0451

ECMO

8 (1.7%)

6 (1.7%)

2 (1.6%)

1.0000

Infection requiring antibiotics

397 (84.1%)

298 (85.4%)

99 (80.5%)

0.2013

SOFA score^b

8 (6–13)

9.0 (6–13)

8.0 (6.0–12)

0.0267

Platelet count, × 10¹¹/L

15 (9–27)

14 (8–24)

20 (12–36)

 < 0.0001

Transfusion-related characteristics

Transfusion Indication

0.0602

Prophylactic without invasive procedure

163 (34.5%)

112 (32.1%)

51 (41.5%)

Prophylactic prior Invasive procedure

309 (65.5%)

237 (67.9%)

72 (58.5%)

Platelet dose, × 10¹¹

3.7 (3.3–4.8)

3.7 (3.3–4.7)

3.7 (3.3–4.8)

0.9069

Apheresis platelet concentrate

155 (32.8%)

119 (34.1%)

36 (29.3%)

0.3268

Pooled platelet concentrate

317 (67.2%)

230 (65.9%)

87 (70.7%)

ABO compatibility^c

347 (77.6%)

256 (76.9%)

91 (79.8%)

0.5145

Maximum platelet storage duration, days

4 (3–5)

5 (4–5)

4 (3–5)

0.0152

Maximum of storage time, > 4days

224 (47.5%)

177 (50.7%)

47 (38.2%)

0.0169

24-h fluid balance, mL^d

825 (− 373–1926)

800 (− 482–1874)

987 (− 200–2000)

0.7883