Table 1 Characteristics of included studies (RCTs)
From: Heterogeneity in defining multiple trauma: a systematic review of randomized controlled trials
All studies n = 50 | Studies that provide a definition n = 31 | Studies that do not provide a definition n = 19 | |
|---|---|---|---|
Number of patients included, mean (min – max) Studies including more than 100 patients, n (%) | 233 (41–1629) 27 (54) | 296 (45–1629) 20 (65) | 128 (41–573) 7 (37) |
Age, years min – max | 31–70 | 31–70 | 32–46 |
ISS, min – max | 11–37 | 11–37 | 19–37 |
Sex, % male, min – max | 27–94 | 56–90 | 27–94 |
Multicenter trials, n (%) | 23 (46) | 18 (58) | 5 (26) |
Type of intervention evaluated, n (%) | |||
Transfusion or hemostasis therapy | 12 (24) | 7 (23) | 4 (21) |
Nutrition | 11 (22) | 6 (19) | 6 (32) |
Fluid or blood pressure strategy | 7 (14) | 4 (13) | 3 (16) |
Surgical therapy | 3 (6) | 2 (6) | 1 (5) |
Imagery | 3 (6) | 3 (10) | 0 |
Other | 14 (28) | 9 (29) | 5 (26) |
Trial presenting with significant results*, n (%) | 13 (32) | 9 (32) | 4 (31) |
Overall ROB, n (%) | |||
Low | 34 (68) | 20 (65) | 14 (74) |
Some concerns | 10 (20) | 6 (19) | 4 (21) |
High | 6 (12) | 5 (16) | 1 (5) |