Table 2 Physiological variables and burden of secondary insults during neurocritical care

Physiological variables

ICP (mmHg), median (IQR)

12 (8–16)

PRx (coefficient), median (IQR)

0.01 (− 0.11–0.14)

CPP (mmHg), median (IQR)

75 (72–79)

CPPopt (mmHg), median (IQR)

75 (71–80)

PbtO₂ (mmHg), median (IQR)

26 (20–28)

Insults

ICP > 20 mmHg (%GMT), median (IQR)

5 (2–20)

ICP > 22 mmHg (%GMT), median (IQR)

3 (1–11)

PRx > 0.00 (%GMT), median (IQR)

51 (38–64)

PRx > 0.30 (%GMT), median (IQR)

23 (15–35)

CPP < 60 mmHg (%GMT), median (IQR)

3 (1–7)

∆CPPopt <  − 5 mmHg (%GMT), median (IQR)

28 (20–36)

∆CPPopt <  −10 mmHg (%GMT), median (IQR)

14 (8–20)

PbtO₂ < 20 mmHg (%GMT), median (IQR)

17 (2–49)

Combined pbtO₂ and global cerebral physiology-insults

PbtO₂ < 20 mmHg and ICP > 20 mmHg for (%GMT), median (IQR)

1 (0–3)

PbtO₂ < 20 mmHg and ICP > 22 mmHg for (%GMT), median (IQR)

0 (0–2)

PbtO₂ < 20 mmHg and PRx > 0.00 (%GMT), median (IQR)

6 (1–21)

PbtO₂ < 20 mmHg and PRx > 0.30 (%GMT), median (IQR)

1 (0–6)

PbtO₂ < 20 mmHg and CPP < 60 mmHg (%GMT), median (IQR)

0 (0–1)

PbtO₂ < 20 mmHg and ∆CPPopt < − 5 mmHg (%GMT), median (IQR)

4 (0–11)

PbtO₂ < 20 mmHg and ∆CPPopt < − 10 mmHg (%GMT), median (IQR)

3 (0–9)