Fig. 2From: Brain tissue oxygen monitoring in traumatic brain injury: part I—To what extent does PbtO2 reflect global cerebral physiology?PbtO2 in relation to cerebral physiological variables depending on the concurrent pressure or oxygen reactivity status—a GAM analysis. Impaired/intact reactivity was defined as PRx above/below 0.30. As illustrated, pbtO2 was generally minimally lower over the ICP-range when pressure autoregulation was impaired. In addition, pbtO2 was slightly lower for CPP below 60–70 mmHg when pressure autoregulation was impaired, but minimally higher for higher CPP-values. Similarly, pbtO2 was slightly lower for negative ∆CPPopt when pressure autoregulation was impaired, but minimally higher for positive ∆CPPopt. CPP cerebral perfusion pressure. GAM generalized additive model, ICP intracranial pressure, PbtO2 partial brain tissue oxygenation, PRx pressure reactivity indexBack to article page