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Fig. 1 | Critical Care

Fig. 1

From: Brain tissue oxygen monitoring in traumatic brain injury: part I—To what extent does PbtO2 reflect global cerebral physiology?

Fig. 1

PbtO2 in relation to cerebral physiological variables—a GAM analysis. In these GAM analyses, pbtO2 remained within 20–30 mmHg over the range of ICP between 0 to 50 mmHg and of PRx between − 1 and + 1. PbtO2 plateaued at 25 mmHg for CPP above 60–70 mmHg, gradually decreased for lower CPP-values, and even went below 20 mmHg when CPP was below 30 mmHg. Similarly, pbtO2 plateaued around 25 mmHg for ∆CPPopt of − 10 mmHg and higher, but went below 20 mmHg for ∆CPPopt below − 30 mmHg. CPP cerebral perfusion pressure, GAM generalized additive model, ICP intracranial pressure, PbtO2 partial brain tissue oxygenation, PRx pressure reactivity index

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