Table 2 Clinical outcomes, endotypes, and severity predictions
Variable | Septic (N = 377)a | Non-septic (N = 145)a | p valueb |
|---|---|---|---|
Secondary infection | 114 (30.2%) | 12 (8.3%) |  < 0.001 |
CCI | 122 (32.4%) | 10 (6.9%) |  < 0.001 |
Adverse outcome | 213 (56.7%) | 40 (27.8%) |  < 0.001 |
 Missing | 1 | 1 |  |
Poor discharge disposition | 152 (40.4%) | 23 (16%) |  < 0.001 |
 Missing | 1 | 1 |  |
In-hospital mortality | 28 (7.4%) | 3 (2.1%) | 0.02 |
30-day mortality | 38 (10.2%) | 6 (4.1%) | 0.03 |
 Missing | 4 | 0 |  |
90-day mortality | 61 (16.8%) | 8 (5.5%) |  < 0.001 |
 Missing | 13 | 0 |  |
Endotype |  |  |  < 0.001 |
 Adaptive | 151 (40.1%) | 74 (51%) |  |
 Coagulopathic | 97 (25.7%) | 48 (33.1%) |  |
 Inflammopathic | 129 (34.2%) | 23 (15.9%) |  |
IMX-SEV severity risk band |  |  |  < 0.001 |
 Low | 38 (10.1%) | 16 (11%) |  |
 Moderate | 250 (66.3%) | 124 (85.5%) |  |
 High | 89 (23.6%) | 5 (3.5%) |  |