Table 3 Test characteristics of endothelial dysfunction marker-based multivariable logistic regression model to estimate risk of D3 SA-AKI in the entire cohort and across predefined groups based on PERSEVERE-II mortality risk

Entire cohort

AUROC

0.78

0.77

True positive, n

52

51

False negative, n

51

52

False positive, n

29

30

True negative, n

165

164

Sensitivity %

50.5%

49.5%

Specificity %

85.1%

84.5%

False positive rate (%)

14.9%

15.5%

False negative rate

49.5%

50.5%

High and intermediate risk P-II strata

AUROC

0.88

0.85

True positive, n

37

35

False negative, n

11

13

False positive, n

9

9

True negative, n

40

40

Sensitivity %

77.1%

72.9%

Specificity %

81.6%

81.6%

False positive rate (%)

18.4%

18.4%

False negative rate (%)

22.9%

27.1%

Low-risk P-II Strata

AUROC

0.77

0.73

True positive, n

16

17

False negative, n

39

38

False positive, n

10

14

True negative, n

135

131

Sensitivity %

29.1%

30.9%

Specificity %

93.1%

90.3%

False positive rate (%)

6.9%

9.7%

False negative rate (%)

70.9%

69.1%