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Table 2 Multivariable logistic regression analysis to test the association between D3 SA-AKI and endothelial dysfunction markers in the derivation cohort

From: Prognostic and predictive value of endothelial dysfunction biomarkers in sepsis-associated acute kidney injury: risk-stratified analysis from a prospective observational cohort of pediatric septic shock

Term

Coefficients (SE)

p value

Adj odds ratio

AUROC

Age (in years)

− 0.04 (0.03)

0.139

0.95 (0.89, 1.01)

0.76

PRISM-III

0.04 (0.02)

0.022

1.04 (1.01, 1.07)

 

PERSEVERE-II mortality probability*

− 0.02 (0.12)

0.842

0.97 (0.77, 1.23)

 

sTM (Log10)

2.93 (0.82)

 < 0.001

18.7 (3.8, 93.2)

 

Angpt-2 (Log10)

1.03 (0.48)

0.022

2.8 (1.1, 7.2)

 

Tie-2 (Log10)

− 1.60 (0.68)

0.019

0.20 (0.05, 0.77)

 
  1. All endothelial dysfunction markers were considered in this model and backward elimination with an alpha of 0.05 was used to select variables
  2. AUROC, Area under the receiver operating characteristic curve
  3. *The raw PERSEVERE-II mortality probability was transformed by a factor of 10 for logistic regression analyses
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Critical Care

ISSN: 1364-8535