Fig. 7
From: Moderate exercise-induced dynamics on key sepsis-associated signaling pathways in the liver
Sepsis increases the Hif1a-signaling target proteins (mTOR, AKT, AMPK, PRKG1, and PDE5a) expression levels in liver tissue, pre-exercise training attenuates this response. A–E, HIF-1α target proteins in males (L) and females (R) stratified by group. F, Western Blots G, compiled quantification data (A–E). G1 = sedentary, G2 = exercise-trained, G3 = exercise trained + sham surgery, G4 = CLP (untrained, tissue harvest at 24 h), G5 = CLP (trained, tissue harvest at 12 h), G6 = CLP (trained, tissue harvest at 24 h)