Fig. 13
From: Moderate exercise-induced dynamics on key sepsis-associated signaling pathways in the liver
Integrative summary of the major observed effect in sepsis and exercise training on liver tissue and serum samples. A The panel shows the overview of the intersection of different potential key impacted Signaling pathways including inflammation, oxidative/nitrergic stress (redox balance), Hypoxia, and AGE/RAGE signaling in both Male and Female sepsis animals. B Pre-exercise training animals at post-operative hour 24. Pre-exercise training (3 weeks treadmill) significantly reduces the sepsis-induced molecular pathways destruction and increases sepsis survival. ↑, increased; ↓, decreased; ↕, no change/not significant change