Table 3 Dose adjustment method according to antibiotics
From: International survey of antibiotic dosing and monitoring in adult intensive care units
Survey question | Response | n (%) |
|---|---|---|
Vancomycin doses are generally adjusted by: (select all that apply) (n = 535) | Clinical judgement of treating physician | 307 (57) |
| Â | Linear adjustment following TDM | 167 (31) |
| Â | Dosing software | 60 (11) |
| Â | Dosing guideline | 178 (33) |
| Â | Other | 25 (5) |
Beta-lactam doses are generally adjusted by: (select all that apply) (n = 506) | Clinical judgement of treating physician | 290 (57) |
| Â | Product information | 159 (31) |
| Â | TDM | 74 (15) |
| Â | Dosing software | 15 (3) |
| Â | Dosing guideline | 129 (25) |
| Â | Pharmacist recommendation | 156 (31) |
| Â | ID/AMS recommendation | 123 (24) |
| Â | Other | 24 (5) |
Aminoglycoside doses are generally adjusted by: (select all that apply) (n = 497) | Clinical judgement of treating physician | 256 (52) |
| Â | Product information | 102 (21) |
| Â | TDM | 178 (36) |
| Â | Dosing software | 38 (8) |
| Â | Dosing guideline | 91 (18) |
| Â | Pharmacist recommendation | 194 (39) |
| Â | ID/AMS recommendation | 107 (22) |
If the peak concentration is below your target, do you: (select all that apply) (n = 325) | Increase the next daily dose | 179 (55) |
| Â | Leave the daily dose unchanged | 19 (6) |
| Â | Administer a supplementary dose | 38 (12) |
| Â | Use dosing software to guide therapy | 45 (14) |
| Â | Unsure | 62 (19) |
If the trough concentration is above your target, do you: (select all that apply) (n = 362) | Leave the daily dose unchanged | 44 (12) |
| Â | Decrease the next daily dose | 137 (38) |
| Â | Delay next dose until the trough is below the target concentration | 78 (22) |
| Â | Extend the dosing frequency | 120 (33) |
| Â | Use dosing software to guide therapy | 43 (12) |