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Table 3 Odds ratios (95% Confidence interval) for in-hospital mortality associated with gender by the site of infection

From: Influence of gender on age-associated in-hospital mortality in patients with sepsis and septic shock: a prospective nationwide multicenter cohort study

Infection type

Number of death (%)

P values

Male versus female

Male

Female

OR (95% CI)*

Respiratory

    

Overall (N = 3007)

666 (33.9)

337 (32.3)

0.35

1.11 (0.94, 1.32)

 Age 19–50 (N = 145)

11 (12.2)

18 (32.7)

< 0.01

0.29 (0.12, 0.69)

 Age 50–80 (N = 3836)

413 (34.2)

147 (28.7)

0.03

1.30 (1.03, 1.64)

 Age > 80 (N = 2194)

242 (36.5)

172 (36.0)

0.86

1.01 (0.78, 1.29)

P for interaction for age

   

< 0.01

Abdominal

    

Overall (N = 1712)

260 (27.2)

178 (23.5)

0.09

1.03 (0.81, 1.31)

 Age 19–50 (N = 132)

20 (25.0)

15 (28.9)

0.63

0.78 (0.34, 1.81)

 Age 50–80 (N = 3142)

185 (27.1)

108 (24.4)

0.32

1.02 (0.76, 1.38)

 Age > 80 (N = 1863)

55 (28.7)

55 (21.1)

0.06

1.07 (0.67, 1.70)

P for interaction for age

   

0.81

Urinary

    

Overall (N = 1369)

101 (18.8)

131 (15.8)

0.15

1.18 (0.87, 1.60)

 Age 19–50 (N = 72)

3 (13.0)

3 (6.5)

0.37

2.11 (0.37, 12.09)

 Age 50–80 (N = 694)

55 (18.3)

50 (13.0)

0.05

1.47 (0.95, 2.27)

 Age > 80 (N = 331)

43 (20.0)

78 (19.5)

0.88

0.91 (0.59, 1.41)

P for interaction for age

   

0.24

Others

    

Overall (N = 292)

50 (32.1)

35 (25.7)

0.24

1.11 (0.59, 2.06)

 Age 19–50 (N = 37)

6 (22.2)

2 (20.0)

0.88

0.86 (0.12, 6.11)

 Age 50–80 (N = 180)

31 (31.3)

19 (23.5)

0.24

1.14 (0.53, 2.44)

 Age > 80 (N = 331)

13 (43.3)

14 (31.1)

0.28

1.01 (0.31, 3.32)

P for interaction for age

   

0.96

  1. For the subgroup analysis by age group, age was not adjusted for
  2. CI confidence interval; ICU intensive care medicine; OR odds ratio; SOFA Sequential Organ Failure Assessment
  3. *Hospital as a stratification factor in logistic models and further adjusted for age, Charlson comorbidity score, initial SOFA score, septic shock, site of infection, type of infection, ICU admission/transfer, and year