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Table 2 Odds ratios (95% confidence interval) for in-hospital mortality associated with gender

From: Influence of gender on age-associated in-hospital mortality in patients with sepsis and septic shock: a prospective nationwide multicenter cohort study

 

Number of death (%)

P-values

Male versus female

Male

Female

OR (95% CI)*

All patients

    

Overall (N = 6442)

1095 (30.0)

690 (24.7)

< 0.01

1.15 (1.02, 1.29)

 Age 19–50 (N = 412)

44 (19.4)

48 (26.0)

0.11

0.57 (0.35, 0.93)

 Age 50–80 (N = 3836)

707 (29.9)

341 (23.1)

< 0.01

1.25 (1.07, 1.47)

 Age > 80 (N = 2194)

344 (32.4)

301 (26.6)

< 0.01

1.10 (0.90, 1.33)

P for interaction for age

   

< 0.01

Without septic shock

    

Overall (N = 5345)

824 (27.3)

523 (22.4)

< 0.01

1.15 (1.01, 1.31)

 Age 19–50 (N = 340)

18 (12.8)

29 (22.3)

0.19

0.66 (0.38, 1.16)

 Age 50–80 (N = 3142)

389 (26.6)

191 (20.9)

< 0.01

1.34 (1.12, 1.60)

 Age > 80 (N = 1863)

179 (28.5)

159 (24.8)

0.02

1.15 (0.93, 1.43)

P for interaction for age

   

0.04

With septic shock

    

Overall (N = 1097)

271 (42.6)

167 (36.2)

0.03

1.12 (0.86, 1.45)

 Age 19–50 (N = 72)

15 (33.3)

14 (51.9)

0.12

0.45 (0.17, 1.22)

 Age 50–80 (N = 694)

173 (40.1)

84 (32.1)

0.04

1.32 (0.95, 1.85)

 Age > 80 (N = 331)

83 (52.2)

69 (40.1)

0.03

1.47 (0.94, 2.31)

P for interaction for age

   

0.10

  1. For the subgroup analysis by age group, age was not adjusted for
  2. CI confidence interval; ICU intensive care medicine; OR odds ratio; SOFA Sequential Organ Failure Assessment
  3. *Hospital as a stratification factor in logistic models and further adjusted for age, Charlson comorbidity score (< 9 and ≥ 9), initial SOFA score, septic shock, site of infection, type of infection, ICU admission/transfer, and year
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Critical Care

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