Table 3 Norepinephrine dose before and first reported after CytoSorb® treatment; MAP levels before and 24 h after CytoSorb® treatment (difference: treatment group—control group)

Sepsis

0.03 (± 0.25)

0.05 [− 0.21; 0.31]

0.00 (± 0.15)

0.02 [− 0.11; 0.14]

2.07 (± 9.31)

1.81 [− 7.18; 10.80]

CPB surgery

0.01 (± 0.01)

0.01 [− 0.01; 0.02]

1.64 (± 2.79)

2.44 [− 0.61; 5.49]

Severe illness

SARS-CoV-2

− 0.03 (± 0.07)

− 0.02 [− 0.06; 0.02]

− 0.01 (± 0.04)

− 0.04 [− 0.10; 0.03]

Cardiac arrest

− 0.16 (± 0.15)

− 0.09 [− 0.35; 0.18]

All studies

− 0.02 (± 0.06)

− 0.02 [− 0.08; 0.04]

0.00 (± 0.02)

− 0.01 [− 0.02; 0.01]

1.51 (± 5.61)

1.12 [− 4.73; 6.97]

1.17 (± 2.65)

1.80 [− 1.07; 4.66]