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Table 2 Management in the intensive care unit and characteristics on discharge

From: Prevalence and risk factors of significant persistent pain symptoms after critical care illness: a prospective multicentric study

 

No or mild symptoms at 3 months

N = 426

Significant symptoms at 3 months

N = 388

P value

SAPS 2

33 (± 16)

32 (± 16)

0.8

Surgery during ICU stay

Intra-cranial

19 (4.5%)

17 (4.4%)

 > 0.9

Spinal

4 (0.9%)

19 (4.9%)

0.001

Orthopaedics

23 (5.4%)

55 (14.2%)

 < 0.001

Intra-abdominal

132 (31%)

107 (27.6%)

0.3

Thoracic

64 (15%)

50 (12.3%)

0.4

Pleural drainage

32 (7.5%)

34 (8.7%)

0.6

Number of interventions during ICU

1 [0–1]

1 [0–1]

0.6

Pain management

Continuous Morphine

196 (46%)

170 (43.8%)

0.6

Remifentanil

41 (9.6%)

51 (13.1%)

0.1

Continuous Ketamine

49 (11.5%)

61 (15.8%)

0.1

Gabapentin, Pregabalin

42 (9.9%)

50 (12.9%)

0.2

Loco-regional anesthesia

84 (19.7%)

98 (25.3%)

0.1

Pain symptoms on discharge

Numeric Rating Scale

2 [1–4]

4 [2 –6]

 < 0.001

ID pain score

0 [0–1]

1 [0–2]

 < 0.001

ID pain score > 3

10 (2.3%)

22 (5.6%)

0.02

Pain location

Head

26 (6.1%)

33 (8.5%)

0.2

Abdominal

105 (24.7%)

101 (26%)

0.8

Limb

61 (14.3%)

86 (22.1%)

0.005

Joint

27 (6.3%)

29 (7.5%)

0.6

Thorax

59 (13.9%)

75 (19.3%)

0.04

Back

23 (5.4%)

60 (15.5%)

 < 0.001

ICU complications

Acute respiratory distress syndrome

45 (10.6%)

39 (10.1%)

0.9

Prone positioning

19 (4.5%)

29 (7.5%)

0.1

Neuro-muscular blocking agents

54 (12.7%)

48 (12.5%)

0.9

Invasive mechanical ventilation duration (days)

0 [0–2]

0 [0–2]

0.5

ICU length of stay (days)

6 [4–12]

6 [4–11]

0.9

  1. Numeric variables are expressed as mean (± SD) or median [1st–3rd quartile]. Numeric variables were expressed as mean (± SD). Continuous outcomes were compared with Student's t-test. Discrete outcomes were compared with chi-squared or Fisher’s (£) exact test
  2. SAPS Simplified Acute Physiological Score, ICU Intensive Care Unit