Pharmacophenotype identification of intensive care unit medications using unsupervised cluster analysis of the ICURx common data model

Table 2 Pair-wise comparison of differences in patient outcomes by patient cluster

1st Cluster	2nd Cluster	Continuous outcomes					Categorical outcomes
1st Cluster	2nd Cluster	Length of stay (days)	Duration of mechanical ventilation (days)	Duration of vasopressor support (days)	APACHE II score (first 24 h)	MRC-ICU	Death	Acute kidney injury	Delirium	Mechanical ventilation
1	2	0.9971	0.0027	0.0136	0.0003	0.1937	0.1316	0.0940	0.7607	0.9279
1	3	0.9760	0.0603	0.0896	0.0107	0.5721	0.4827	1.0000	0.3018	0.3824
1	4	0.1559	0.6876	0.9624	0.8643	0.4727	0.3311	0.3620	0.1300	0.3724
1	5	0.0258	0.0002	0.0011	0.1407	0.2410	0.7143	0.1823	1.0000	0.4903
2	3	0.8934	0.2221	0.3854	0.1563	0.3545	0.0397	0.1705	0.2018	0.3226
2	4	0.1686	0.0867	0.0488	0.0019	0.6489	0.2090	0.0225	0.2979	0.3633
2	5	0.0355	0.2300	0.2499	0.1904	0.9259	0.4891	1.0000	0.8963	0.5597
3	4	0.1278	0.1279	0.1613	0.0368	0.8586	0.7040	0.3835	0.0220	1.0000
3	5	0.0257	0.0185	0.0539	0.8206	0.4115	0.3628	0.2390	0.3939	0.1748
4	5	0.4197	0.0053	0.0077	0.1781	0.6249	0.2370	0.0472	0.2451	0.1797

This analysis summarizes the significant differences observed between two patient clusters (e.g., Cluster 1 and Cluster 2) for various outcomes

ISSN: 1364-8535