Clinical risk factors for increased respiratory drive in intubated hypoxemic patients

Table 1 Baseline demographics and clinical characteristics

	All patients (n = 217)
Demographics
Men, No. (%)	153 (71)
Age, years	65 [53–75]
BMI, kg/m²	26 [23–29]
Recent medical history
Intubation days, median [Q1–Q3]	3 [2–5]
SAPS II, median [Q1–Q3]	41 [31–52]
Etiology
Pneumonia, No. (%)	127 (58)
Aspiration of gastric content, No. (%)	20 (9)
Non-pulmonary sepsis, No. (%)	37 (17)
Other^, No. (%)	54 (25)
Lung injury
Bilateral Infiltrates (ARDS diagnosis) No. (%)	102 (47)
PaO₂/FiO₂, mmHg	228 [190–254]
Clinical status and ventilation settings on day 1
SOFA	6 [4–8]
RASS	− 1 [− 1 to 0]
PEEP, cmH₂O	8 [7–10]
Pressure support, cmH₂O	8 [6–12]
Addition of sigh breaths, No. (%)	109 (50)
FiO₂	0.4 [0.3–0.4]

Data are expressed as median [Q₁–Q₃] or as number (%), as appropriate
BMI: Body mass index; SAPS II: Simplified Acute Physiology Score II; ARDS: acute respiratory distress syndrome; SOFA: Sequential Organ Failure Assessment Score; RASS: Richmond Agitation Sedation Scale; PEEP: positive end-expiratory pressure
^“Other” includes lung contusion, lung vasculitis, drowning, pancreatitis, severe burns, major trauma, TRALI or other conditions

ISSN: 1364-8535