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Fig. 1 | Critical Care

Fig. 1

From: Serum-integrated omics reveal the host response landscape for severe pediatric community-acquired pneumonia

Fig. 1

Study overview. A Study overview. 50 subjects including 20 S-CAPs, 15 NS-CAPs and 15 CONs from cohort 1 were recruited for proteomic and metabolomic analysis. Nine DAPs were verified with ELSIA in cohort 1. The DAPs and DAMs were then used to identify potential biomarker combinations for severe CAP diagnosis. B Selected biomarkers were verified using an independent cohort with 129 blinded subjects (cohort 2). C Protein-metabolite crosstalk was examined using integrated analysis. Proteomic and metabolomic signatures were analyzed to uncover the molecular profile for severe CAP

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Critical Care

ISSN: 1364-8535