Table 1 Demographic and clinical characteristics of the study population

Male sex, %

58

Age, years

69 (54–76)

Height, cm, mean (SD)

172 (10)

ICU admission total body weight, kg

76 (64–85)

ICU admission BMI, kg/m²

25.3 (23.4–28.9)

Admission details

APACHE II score, mean (SD)

21 (10)

Hospital admission duration, days

19 (9–33)

Hospital mortality, %

39

ICU admission duration, days

6 (2–17)

ICU mortality, %

26

Mechanical ventilation, %

55

Sepsis, %

48

Tertiary referral ICU, %

23

Laboratory values

Albumin serum at ICU admission, g/L, mean (SD)

25.8 (8.5)

Albumin serum, g/L, mean (SD)

23.3 (8.2)

Creatinine serum at ICU admission, µmol/L

82 (63–159)

Creatinine serum, µmol/L

82 (66–222)

Creatinine clearance^a at ICU admission, mL/min/1.73m², mean (SD)

68 (42)

Creatinine clearance^a, mL/min/1.73m², mean (SD)

66 (42)

Flucloxacillin dose prescribedb

6 g per 24 h cont, %

24

9 g per 24 h cont, %

6

12 g per 24 h cont, %

44

1 g q6h, %

6

1 g q4h, %

9

2 g q4h, %

12