Table 2 Comparison of metabolic parameters between the two groups
| Â | Control | Intervention | p |
|---|---|---|---|
n = 159 | n = 163 | ||
Sodium, mmol/L | |||
Before inclusion | 140 (3.9) | 140.4 (4.6) | 0.42 |
Day 1 | 145 (5.7) | 151.9 (4.9) |  < 0.001 |
Day 2 | 145.6 (6.3) | 154.1 (5.4) |  < 0.001 |
Day 3 | 146.3 (6.5) | 153.8 (5.8) |  < 0.001 |
Day 4 | 145.9 (6.4) | 151.7 (6.2) |  < 0.001 |
Chloride, mmol/L | |||
Before inclusion | 106.5 (5.2) | 107.3 (5.4) | 0.18 |
Day 1 | 113.6 (6) | 120.8 (8.1) |  < 0.001 |
Day 2 | 114.5 (6.4) | 122.8 (8.6) |  < 0.001 |
Day 3 | 114.6 (8.8) | 121 (8.5) |  < 0.001 |
Day 4 | 111.6 (10.7) | 117.9 (9) |  < 0.001 |
Arterial pH | |||
Before inclusion | 7.34 (0.09) | 7.34 (0.09) | 0.97 |
Day 1 | 7.37 (0.08) | 7.36 (0.06) | 0.46 |
Day 2 | 7.40 (0.07) | 7.39 (0.07) | 0.22 |
Day 3 | 7.41 (0.07) | 7.42 (0.06) | 0.24 |
Day 4 | 7.43 (0.05) | 7.42 (0.07) | 0.58 |
Base deficit, mmol/L | |||
Before inclusion | − 3.7 (3.7) | − 3.5 (3.7) | 0.56 |
Day 1 | − 2.7 (3.6) | − 2.7 (3.1) | 0.97 |
Day 2 | − 0.47 (2.9) | − 0.96 (2.9) | 0.13 |
Day 3 | 1.2 (2.7) | 0.9 (2.5) | 0.28 |
Day 4 | 2.3 (3.3) | 2.4 (3) | 0.98 |
Bicarbonate, mmol/L | |||
Before inclusion | 21.7 (3.4) | 22.1 (2.8) | 0.28 |
Day 1 | 16.4 (10.8) | 17 (10.1) | 0.62 |
Day 2 | 23.5 (3.2) | 23.1 (2.6) | 0.25 |
Day 3 | 25.1 (3.1) | 24.9 (2.3) | 0.59 |
Day 4 | 27 (5) | 27.2 (4.3) | 0.70 |
Lactate, mmol/L | |||
Before inclusion | 2.4 (2.3) | 2.3 (1.7) | 0.51 |
Day 1 | 1.8 (1.2) | 1.6 (0.8) | 0.21 |
Day 2 | 1.4 (0.8) | 1.5 (1) | 0.75 |
Day 3 | 1.3 (0.5) | 1.3 (0.6) | 0.58 |
Day 4 | 1.2 (0.49) | 1.2 (1) | 0.90 |