From: Perioperative changes in fluid distribution and haemodynamics in acute high-risk abdominal surgery
Variables | Preoperative | 6 h post-operative | Mean difference | P value (Wilcox) |
---|---|---|---|---|
All patients | ||||
TBW, L | 39.8 ± 8.1 | 41.0 ± 8.2 | 0.1 ± 4.9 | 0.430 |
ICW, L | 21.4 ± 5.0 | 21.4 ± 5.1 | − 1.0 ± 2.5 | 0.876 |
ECW, L | 18.3 ± 3.8 | 19.8 ± 4.0 | 1.5 ± 1.7 | 0.022 |
ECW/ICW ratio | 0.87 ± 0.2 | 0.96 ± 0.2 | – | |
AFO, L | 0.68 ± 2.5 | 2.4 ± 2.7 | 1.77 ± 1.4 | < .0001 |
RFO, median (IQR), % | 3.1 (− 5.7–11.7) | 9.5 (4.3–22.2) | – | 0.0001 |
Patients with overhydration, n (%) | 12 (16.4) | 26 (36.0) | – | < .0001** |
Intestinal obstruction patients | ||||
TBW, L | 40.1 ± 7.8 | 40.5 ± 7.9 | 0.4 ± 2.5 | 0.802 |
ICW, L | 22.2 ± 4.8 | 21.2 ± 5.0 | 1.0 ± 1.7 | 0.287 |
ECW, L | 17.9 ± 3.5 | 19.1 ± 3.5 | 1.2 ± 1.8 | 0.197 |
ECW/ICW ratio | 0.82 ± 0.1 | 0.92 ± 0.2 | – | |
AFO, L | − 0.2 ± 2.2 | 1.9 ± 2.6 | 2.0 ± 1.8 | 0.003 |
RFO, median (IQR), % | − 0.5 (− 9.0–7.8) | 7.7 (0.5–16.7) | – | 0.003 |
Patients with overhydration, n (%) | 3 (11.1) | 8 (29.6) | – | 0.004** |
Perforated viscus patients | ||||
TBW, L | 38.7 ± 9.1 | 41.4 ± 8.7 | 2.7 ± 4.2 | 0.308 |
ICW, L | 20.3 ± 5.9 | 21.6 ± 5.8 | 1.2 ± 2.7 | 0.404 |
ECW, L | 18.2 ± 4.1 | 20.0 ± 6.7 | 1.8 ± 2.0 | 0.107 |
ECW/ICW ratio | 0.93 ± 0.2 | 0.96 ± 0.2 | – | |
AFO, L | 1.0 ± 2.8 | 2.5 ± 3.0 | 1.5 ± 1.3 | 0.046 |
RFO, median (IQR), % | 5.1 (− 3.0–13.8) | 10.9 (2.4–23.7) | – | 0.035 |
Patients with overhydration, n (%) | 6 (23.1) | 10 (38.5) | – | 0.0004** |
Anastomotic leakage patients | ||||
TBW, L | 40.7 ± 7.3 | 40.7 ± 8.3 | 0.0 ± 7.0 | 0.241 |
ICW, L | 21.7 ± 4.0 | 21.4 ± 4.5 | − 0.3 ± 2.7 | 0.247 |
ECW, L | 19.0 ± 3.9 | 20.4 ± 3.4 | 1.4 ± 1.2 | 0.261 |
ECW/ICW ratio | 0.88 ± 0.1 | 1.0 ± 0.2 | – | |
AFO, L | 1.5 ± 2.1 | 3.1 ± 1.9 | 2.0 ± 1.0 | 0.083 |
RFO, median (IQR), % | 5.8 (− 2.0–14.1) | 11.9 (8.5–22.8) | – | 0.011 |
Patients with overhydration, n (%) | 3 (15.0) | 8 (40.0) | – | 0.024** |