Table 1 Baseline characteristics of the ICU study populations aged ≤ 52 years stratified by sex
|  | Acute myocardial infarction age ≤ 52 years | Stroke age ≤ 52 years | ||||||
|---|---|---|---|---|---|---|---|---|
Overall n = 13,449 | Men n = 11,218 (83.4%) | Women n = 2231 (16.6%) | p-value | Overall n = 3505 | Men n = 2116 (60.4%) | Women n = 1389 (39.6%) | p-value | |
Age (years), mean ± SD | 45 ± 5.4 | 45 ± 5.4 | 45 ± 5.7 | 0.229 | 43 ± 7.9 | 44 ± 7.3 | 41 ± 8.5 |  < 0.001 |
Transfer from other hospital, n (%) | 3140 (23.3) | 2646 (23.6) | 494 (22.1) | 0.176 | 482 (13.8) | 277 (13.1) | 205 (14.8) | 0.353 |
Direct admissions, n (%) | 9684 (72.0) | 8042 (71.7) | 1642 (73.6) | Â | 2591 (73.9) | 157 74.3) | 1018 (73.3) | Â |
Other, n (%) | 625 (4.6) | 530 (4.7) | 95 (4.3) | Â | 432 (12.3) | 266 (12.6) | 166 (12.0) | Â |
SAPS II (points) - mean ± SD | 18.37 ± 9.32 | 18.34 ± 9.26 | 18.53 ± 9.61 | 0.382 | 20.16 ± 12.25 | 20.47 ± 12.47 | 19.69 ± 11.9 | 0.061 |
NEMS score (points) | Â | Â | Â | Â | Â | Â | Â | Â |
  1st shift, mean ± SD | 17.68 ± 7.93 | 17.80 ± 8.00 | 17.05 ± 7.56 |  < 0.001 | 17.72 ± 8.92 | 17.8 ± 8.98 | 17.61 ± 8.82 | 0.542 |
  Average NEMS/shift, mean ± SD | 16.72 ± 6.44 | 16.81 ± 6.40 | 16.3 ± 6.58 |  < 0.001 | 17.91 ± 7.92 | 18 ± 7.43 | 17.78 ± 8.61 | 0.436 |
LOS (days), median (IQR) | 0.93 (0.66–1.44) | 0.94 (0.67–1.45) | 0.9 (0.61–1.42) | 0.273 | 1.16 (0.86–2.06) | 1.16 (0.87–2.09) | 1.18 (0.84–2.01) | 0.624 |
Deaths, n (%) | 62 (0.46) | 50 (0.45) | 12 (0.54) | 0.678 | 77 (2.2) | 44 (2.08) | 33 (2.38) | 0.640 |
Interventions before ICU admission |  |  |  |  < 0.001 |  |  |  | 0.485 |
  PCI, n (%) | 7303 (54.3) | 6222 (55.46) | 1081 (48.45) |  | 31 (0.88) | 20 (0.95) | 11 (0.79) |  |
  Neurovascular interventions, n (%) | 9 (0.07) | 8 (0.07) | 1 (0.04) |  | 511 (14.58) | 312 (14.74) | 199 (14.33) |  |
  CABG surgery, n (%) | 1093 (8.13) | 987 (8.8) | 106 (4.75) |  | 1 (0.03) | 1 (0.05) | 0 (0) |  |
  Heart valve surgery, n (%) | 26 (0.19) | 18 (0.16) | 8 (0.36) |  | 1 (0.03) | 1 (0.05) | 0 (0) |  |
  Aortic surgery, n (%) | 2 (0.01) | 1 (0.01) | 1 (0.04) |  | 1 (0.03) | 1 (0.05) | 0 (0) |  |
  Cardiovascular unspecified, n (%) | 209 (1.55) | 173 (1.54) | 36 (1.61) |  | 100 (2.85) | 52 (2.46) | 48 (3.46) |  |
  Other, n (%) | 279 (2.07) | 226 (2.01) | 53 (2.38) |  | 389 (11.1) | 230 (10.87) | 159 (11.45) |  |
  None, n (%) | 4485 (33.35) | 3556 (31.7) | 929 (41.64) |  | 2452 (69.96) | 1492 (70.51) | 960 (69.11) |  |
Interventions during ICU stay | Â | Â | Â | Â | Â | Â | Â | Â |
  Interventions performed outside the ICU, n (%)* | 3383 (25.15) | 2838 (25.3) | 545 (24.43) | 0.402 | 1454 (41.48) | 899 (42.49) | 555 (39.96) | 0.147 |
  Interventions performed inside the ICU, n (%)** | 770 (5.73) | 622 (5.54) | 148 (6.63) | 0.049 | 769 (21.94) | 461 (21.79) | 308 (22.17) | 0.818 |
Mechanical ventilatory support, n (%) | 1515 (11.26) | 1330 (11.86) | 185 (8.29) |  < 0.001 | 673 (19.2) | 425 (20.09) | 248 (17.85) | 0.111 |
Supplementary ventilatory care***, n (%) | 8862 (65.89) | 7483 (66.71) | 1379 (61.81) |  < 0.001 | 1710 (48.79) | 1078 (50.95) | 632 (45.5) | 0.002 |
Vasoactive agents | Â | Â | Â | Â | Â | Â | Â | Â |
  One, n (%) | 2957 (21.99) | 2520 (22.46) | 437 (19.59) | 0.003 | 990 (28.25) | 595 (28.12) | 395 (28.44) | 0.868 |
  Multiple, n (%) | 684 (5.09) | 594 (5.3) | 90 (4.03) | 0.015 | 233 (6.65) | 144 (6.81) | 89 (6.41) | 0.694 |
Renal replacement therapy, n (%) | 119 (0.88) | 94 (0.84) | 25 (1.12) | 0.239 | 13 (0.37) | 8 (0.38) | 5 (0.36) | 1 |