Table 1 Patient characteristics
From: Intraoperative extracorporeal blood purification therapy during major septic vascular surgery
Patient | 1 | 2 | 3 | 4 | 5 | 6 |
|---|---|---|---|---|---|---|
Age (years) | 78 | 18 | 58 | 75 | 61 | 68 |
Comorbidities | Diabetes Solid tumor KB infection | Denutrition Multiple ECMO complications (CCA after PE) | Denutrition Ischemic cardiopathy OALL | Hypertension Aorto-enteric fistula | Denutrition Hypertension Solid tumor OALL | Hypertension Diabetes COPD |
Medical history | ||||||
Previous graft | Aortic endograft for mycotic pseudoaneurysm | Ilio-femoral prosthetic graft for bypass rupture | Aorto-bifemoral graft | Aortic endograft for aorto-enteric fistula | Aorto-bifemoral graft | Aorto-bifemoral graft |
Preoperative characteristics | Disseminated KB infection | Chronic sepsis, hospitalized in ICU for 4 months | Groin infection with wound leaking | Fistula between endograft and duodenum | Groin infection: drainage and NPWT | Groin and aortic graft infection |
Surgical information | ||||||
Surgery description | Endograft removal with aorto-biiliac CAA reconstruction | Graft removal with in situ CAA reconstruction | Graft removal with CAA reconstruction | Endograft removal with CAA reconstruction + intestinal procedure | Graft removal with CAA reconstruction | Graft removal with CAA reconstruction |
Surgery duration (minutes) | 259 | 253 | 303 | 396 | 381 | 362 |
Aortic clamping duration (minutes) | 80 | 89 | 72 | 71 | 101 | 102 |
Anesthesia information | ||||||
Red blood cell units (n) | 3 | 2 | 2 | 2 | 2 | 0 |
Crystalloids (mL) | 8600 | 3000 | 6500 | 7000 | 11,000 | 5000 |
Maximal norepinephrine dose (μg/kg/min) | 0.9 | 0.4 | 1,7 | 0.4 | 0.8 | 0.4 |
Worst intraoperative pH | 7.14 | 7.26 | 7.18 | 7.29 | 7.24 | 7.25 |
End-of-surgery K+ level (mmol/L) | 4.3 | 4.1 | 5.5 | 3.3 | 4.2 | 5.2 |
End-of-surgery lactate level (mmol/L) | 5.4 | 3.1 | 3.8 | 3.7 | 5.9 | 2.9 |
Outcomes | ||||||
Postoperative MV duration (hours) | 48 | 5 | 20 | 3 | 48 | 6 |
Postoperative RRT duration (h) | 30 | 0 | 24 | 16 | 16 | 46 |
Postoperative vasopressors duration (days) | 1 | 0 | 3 | 2 | 3 | 1 |
ICU LOS (days) | 6 | 17 | 4 | 7 | 11 | 3 |
Hospital LOS (days) | 17 | 146 | 11 | 17 | 20 | 27 |
Adverse events | ||||||
Intraoperative complications | None | None | None | Ionized hypocalcemia 1.06 mmol/L | Ionized hypocalcemia 0.93 mmol/L | Ionized hypocalcemia 1.08 mmol/L |
Postoperative complications | At 4 months, relapse of aortic infection with KB | Pursuit of NPWT | None | None | Mesenteric ischemia at POD 6 | None |
Status at 3 months | Alive | Alive | Alive | Alive | Alive | Alive |