Table 1 Demographics and clinical characteristics of the patients at the baseline
Characteristics | T-piece SBT (n = 54) | High-flow oxygen SBT (n = 54) |
|---|---|---|
Age, years | 66.3 ± 12.1 | 67.8 ± 10.0 |
Male sex | 32 (59.3) | 38 (70.4) |
Body mass index, kg/m2 | 22.9 ± 4.2 | 21.8 ± 3.6 |
Length of MV before SBT, days | 4.0 (2.6–6.9) | 3.9 (2.5–6.0) |
APACHE II score at ICU admission | 20 ± 7 | 18 ± 7 |
Sequential Organ Failure Assessment score | 6.2 ± 3.4 | 6.0 ± 3.9 |
Reason for intubation | ||
 Respiratory failure | 31 (57.4) | 38 (70.4) |
 Nonrespiratory, cardiogenic | 10 (18.5) | 7 (13.0) |
 Nonrespiratory, sepsis | 7 (13.0) | 4 (7.4) |
 Nonrespiratory, others | 6 (11.1) | 5 (9.3) |
Comorbidity | ||
 Cardiovascular disease | 7 (13.0) | 10 (18.5) |
 Chronic respiratory disease | 12 (22.2) | 17 (31.5) |
 Diabetes mellitus | 18 (33.3) | 19 (35.2) |
 Solid malignancy | 26 (48.1) | 24 (44.4) |
 Hematologic malignancy | 16 (29.6) | 8 (14.8) |
 Neurologic disease | 3 (5.6) | 8 (14.8) |
 Chronic kidney disease | 6 (11.1) | 7 (13.0) |
 Chronic liver disease | 7 (13.0) | 11 (20.4) |
Charlson comorbidity index | 5.8 ± 2.6 | 6.4 ± 2.7 |
Baseline physiological variables | ||
 Arterial blood pH | 7.47 ± 0.05 | 7.46 ± 0.04 |
 PaO2/FiO2, mm Hg | 321 (258–386) | 294 (218–390) |
 PaCO2, mm Hg | 35.9 ± 5.4 | 37.6 ± 6.4 |
 Lactate, mmol/L | 1.9 (1.4–2.5) | 1.4 (1.1–2.2) |