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Table 5 Parameters include baseline characteristics, microbiological identification, management and impact of mediastinitis in surviving and dead patients

From: Post-cardiac surgery fungal mediastinitis: clinical features, pathogens and outcome

Characteristics

Survivors (n = 17)

Non-survivors (n = 23)

p

OR

Age (yo)

59 [43–65]

65 [61–73]

0.013

1.1 [1.02–1.19]

Male

14 (82)

18 (78)

1

 

BMI (kg/m2)

24 [20–26]

30 [24–32]

0.028

1.21 [1.01–1.47]

Euroscore II (%)

12 [4.2–19.4]

11.7 [4.6–25]

0.84

 

SAPS II

37 [28–40]

54 [34–61]

0.012

1.07 [1–1.7]

Admission SOFA

9 [5–11]

9 [6–10]

0.93

 

Comorbidity n (%)

Chronic Heart failure

12 (70)

17 (74)

1

 

COPD

2 (11)

5 (21)

0.68

 

Chronic kidney disease

3 (18)

3 (13)

0.79

 

 Dialysis

1 (6)

0 (0)

0.42

 

Diabetes mellitus

8 (47)

12 (52)

0.75

 

 Insulin

5 (29)

5 (21)

0.57

 

Immunosuppression

3 (18)

2 (9)

0.63

 

Heart transplanted

2 (11)

2 (9)

1

 

Recent hospitalization (< 3 months)

10 (59)

12 (52)

0.68

 

Active Smokers

4 (24)

5 (21)

1

 

Initial surgery

Type of surgery, n (%)

 CABG

3 (18)

6 (27)

0.52

 

 Valve replacement

4 (24)

5 (22)

1

 

 Combined (CABG + valve)

1 (6)

4 (17)

0.37

 

 Heart transplantation

8 (47)

4 (17)

0.08

 

 LVAD

1 (6)

1 (4)

1

 

 Other

2 (12)

1 (4)

0.56

 

 Surgery duration (min)

354 [281–397]

278 [172–457]

0.19

 

 CBP duration (min)

186 [138–211]

133 [86–185]

0.19

 

 ACC duration (min)

107[69–166]

87 [51–116]

0.09

 
  1. Significant values are provided in bold
  2. Data are expressed as number (percentage) or median [IQR], as appropriate
  3. BMI Body mass index, SAPSII Simplified acute physiology score II, SOFA Sequential organ failure assessment, COPD chronic obstructive pulmonary disease, LVAD Left ventricular assist device, CABG Coronary artery bypass graft, CPB cardiopulmonary bypass, ACC Aortic cross-clamping