Table 2 Sedative and Analgesic management

Received dexmedetomidine, n (%)^§

49 (96.1)

2 (3.8)

 < 0.01

Received midazolam, n (%)

17 (33.3)

30 (57.7)

0.01

Received propofol, n (%)

43 (84.3)

48 (92.3)

0.21

Received fentanyl, n (%)

50 (98)

49 (94.2)

0.32

Received morphine, n (%)

11 (21.6)

18 (34.6)

0.14

Duration of dexmedetomidine infusion (days)

4 [2–7]

–

–

Duration of midazolam infusion (days)

1 [1–4]

3 [2–4]

0.04

Duration of propofol infusion (days)

5 [2–8]

4 [2–8]

0.96

Duration of fentanyl infusion (days)

6 [3–9]

6 [3–9]

0.89

Duration of morphine infusion (days)

1 [1–2]

2.5 [2–7]

0.05

Median dexmedetomidine dose (mcg/kg/day)

9.01 [5.0–14.8]

–

–

Median midazolam dose (mg/kg/day)

0.14 [0.08–0.38]

0.46 [0.20–0.93]

0.01

Median propofol dose (mg/kg/day)

7.26 [4.01–15.1]

9.38 [6.24–14.9]

0.38

Median fentanyl dose (mcg/kg/day)

12.2 [8.29–15.8]

11.1 [7.5–15.2]

0.58

Median morphine dose (mg/kg/day),

0.42 [0.07–0.81]

0.71 [0.15–1.7]

0.31

Sedation Index during first 48 h (RASS)*

2.08 [1.5–3.0]

2.26 [1.52–3.56]

0.45

Sedation Index while ventilated (RASS)*

1.91 [1.36–2.43]

2 [1.35–2.35]

0.4

Duration of ventilation (days)

3.73 [1.89–7.73]

5.07 [2.43–10.4]

0.91