Variables | No/mild CKD group | Severe CKD group | OR [IC 95%] | p value |
---|---|---|---|---|
Patients, n | 96 | 26 | ||
Female, n (%) | 46 (47.9) | 11 (42.3) | 0.80 [0.33–1.81] | 0.61 |
Age, years | 61 [48.5; 66] | 70.5 [62; 76] | 1.04 [1.01–1.08] | 0.02 |
BMI at ICU admission, kg/m2 | 28 [24.2; 34] | 26.3 [22; 31.8] | 0.97 [0.9–1.05] | 0.41 |
SOFA score at RRT initiation, points | 15 [11.5; 17.5] | 10.5 [7; 14] | 0.85 [0.77; 0.93] | < .01 |
SAPS II at ICU admission, points | 61 [51.5; 80] | 57 [42; 77] | 0.99 [0.96–1.01] | 0.24 |
Intermittent modality for the first RRT, n (%) | 53 (55.2) | 18 (69.2) | 1.82 [0.72–4.6] | 0.20 |
Only intermittent modality for RRT, n (%) | 43 (44.8) | 16 (61.5) | 1.97 [0.81–4.79] | 0.13 |
Only continuous modality for RRT, n (%) | 23 (24) | 4 (15.4) | 0.87 [0.22–3.45] | 0.84 |
RRT period, days | 20 [8; 35] | 29.5 [10; 45] | 1.01 [0.99–1.03] | 0.35 |
RRT sessions, n | 5 [2; 10] | 7.5 [2; 12] | 1.02 [0.97–1.07] | 0.48 |
Intermittent RRT sessions, n | 4 [2; 8] | 5 [2; 11] | 1.02 [0.96–1.08] | 0.52 |
Continuous RRT sessions, n | 3 [2; 6] | 5 [1; 8] | 1.04 [0.93–1.16] | 0.46 |
Underlying condition | ||||
No comorbidity, n (%) | 23 (24) | 10 (38.5) | 1.98 [0.79–4.97] | 0.14 |
Insulin-dependent diabetes, n (%) | 11 (11.5) | 5 (19.2) | 1.84 [0.58–5.87] | 0.30 |
Chronic hypertension, n (%) | 37 (38.5) | 10 (38.5) | 0.99 [0.41–2.43] | 0.99 |
Hematological malignancy, n (%) | 10 (10.4) | 0 (0) | ||
Cirrhosis, n (%) | 7 (7.3) | 0 (0) | ||
Metastatic cancer, n (%) | 1 (1) | 0 (0) | ||
Chronic kidney disease*, n (%) | 2 (2.1) | 2 (7.7) | 4.08 [0.78–21.37] | 0.10 |
Chronic respiratory failure with oxygen therapy, n (%) | 2 (1.8) | 3 (10.3) | 3.92 [0.52–29.25] | 0.18 |
Chronic heart failure NYHA III or IV, n (%) | 12 (12.5) | 1 (3.8) | 0.28 [0.03–2.26] | 0.23 |
Immunosuppression**, n (%) | 7 (7.3) | 4 (15.4) | 2.31 [0.62–8.6] | 0.21 |
Main symptom at ICU admission | ||||
Septic shock, n (%) | 30 (31.3) | 7 (26.9) | 0.81 [0.31–2.13] | 0.67 |
Coma, n (%) | 2 (2.1) | 1 (3.8) | 1.88 [0.16–21.58] | 0.61 |
Acute respiratory distress, n (%) | 17 (17.7) | 6 (23.1) | 1.39 [0.49–3.99] | 0.54 |
Acute kidney injury, n (%) | 18 (18.8) | 5 (19.2) | 1.03 [0.34–3.11] | 0.96 |