Table 1 Characteristics of study population and comparison between no/mild chronic kidney disease and severe chronic kidney disease groups at 3 months
Variables | Study population | No/mild CKD group | Severe CKD group | OR [IC 95%] | p value |
|---|---|---|---|---|---|
Patients, n | 183 | 136 | 47 | ||
Female, n (%) | 78 (42.6) | 58 (42.6) | 20 (42.6) | 0.99 [0.51–1.95] | 0.99 |
Age, years | 62 [54–72] | 61 [53.5–69.5] | 65 [56–73] | 1.02 [0.99–1.04] | 0.23 |
BMI at ICU admission, kg/m2 | 26.9 [23.3–33] | 27.5 [23.2–33] | 26.1 [23.5–33.2] | 0.98 [0.92–1.04] | 0.47 |
SOFA score at RRT initiation, points | 14 [11–17] | 15 [11–18] | 11 [7–15] | 0.88 [0.82–0.94] | < 0.01 |
SAPS II at ICU admission, points | 63 [50–80] | 64 [51–80] | 57 [45–76] | 0.98 [0.97–1] | 0.09 |
Intermittent modality for the first RRT, n (%) | 106 (57.9) | 78 (57.4) | 28 (59.6) | 1.09 [0.56–2.15] | 0.79 |
Only intermittent modality for RRT, n (%) | 90 (49.2) | 65 (47.8) | 25 (53.2) | 1.14 [0.54–2.47] | 0.71 |
Only continuous modality for RRT, n (%) | 37 (20.2) | 29 (21.3) | 8 (17) | 0.83 [0.31–2.23] | 0.71 |
RRT period, days | 20 [8–42] | 18 [7–35] | 36 [10–56] | 1.02 [1.01–1.03] | < 0.01 |
RRT sessions, n | 6 [2–11] | 5 [2–10] | 7 [3–16] | 1.03 [1–1.07] | 0.05 |
Intermittent RRT sessions, n | 4 [2–8] | 4 [2–8] | 5 [3–11] | 1.04 [0.99–1.08] | 0.12 |
Continuous RRT sessions, n | 3 [2–7] | 3 [2–6] | 4.5 [2–12] | 1.05 [0.98–1.13] | 0.14 |
Underlying condition | |||||
No comorbidity, n (%) | 45 (24.6) | 30 (22.1) | 15 (31.9) | 1.66 [0.79–3.46] | 0.18 |
Insulin-dependent diabetes, n (%) | 24 (13.1) | 16 (11.8) | 8 (17) | 1.54 [0.61–3.87] | 0.36 |
Chronic hypertension, n (%) | 76 (41.5) | 59 (43.4) | 17 (36.2) | 0.74 [0.37–1.47] | 0.39 |
Hematological malignancy, n (%) | 18 (9.8) | 14 (10.3) | 4 (8.5) | 0.81 [0.25–2.6] | 0.72 |
Cirrhosis, n (%) | 13 (7.1) | 11 (8.1) | 2 (4.3) | 0.50 [0.11–2.37] | 0.39 |
Metastatic cancer, n (%) | 3 (1.6) | 2 (1.5) | 1 (2.1) | 1.46 [0.13–16.44] | 0.76 |
Chronic kidney disease*, n (%) | 12 (6.6) | 5 (3.7) | 7 (14.9) | 4.58 [1.38–15.24] | 0.01 |
Chronic respiratory failure with oxygen therapy, n (%) | 6 (3.3) | 3 (2.2) | 3 (6.4) | 3.02 [0.59–15.52] | 0.19 |
Chronic heart failure NYHA III or IV, n (%) | 21 (11.5) | 18 (13.2) | 3 (6.4) | 0.45 [0.13–1.59] | 0.21 |
Immunosuppression**, n (%) | 17 (9.3) | 10 (7.4) | 7 (14.9) | 2.20 [0.79–6.17] | 0.13 |
Main symptom at ICU admission | |||||
Septic shock, n (%) | 57 (31.1) | 46 (33.8) | 11 (23.4) | 0.59 [0.28–1.28] | 0.19 |
Coma, n (%) | 6 (3.3) | 5 (3.7) | 1 (2.1) | 0.57 [0.06–5] | 0.61 |
Acute respiratory distress, n (%) | 33 (18) | 23 (16.9) | 10 (21.3) | 1.33 [0.58–3.05] | 0.50 |
Acute kidney injury, n (%) | 38 (20.8) | 26 (19.1) | 12 (25.5) | 1.45 [0.66–3.17] | 0.35 |