Table 2 Corticotropin-stimulated steroid profiles in placebo patients with sepsis and healthy individuals: peak concentrations and dynamic response to corticotropin
|  | Sepsis Placebo Non-survivors (n = 12) | Sepsis Placebo survivors (n = 78) | Healthy volunteers (n = 20) | ||||||
|---|---|---|---|---|---|---|---|---|---|
|  | Median [µg/L] | Quartiles [µg/L] | x-fold increase | Median [µg/L] | Quartiles [µg/L] | x-fold increase | Median [µg/L] | Quartiles [µg/L] | x-fold increase |
11-Desoxycorticosterone | 0.3 | 0.2–0.8 | 4.2 | 0.4* | 0.2–0.9 | 6.8 | 0.2 | 0.1–0.3 | 8.1 |
11-Desoxycortisol | 4.6* | 1.2–21.4 | 4.2 | 3.0* | 1.6–6.3 | 6.2* | 1.0 | 0.5–1.1 | 3,8 |
17-OH-Progesterone | 2.2 | 0.8–3.4 | 4.3 | 1.8* | 1.3–3.1 | 6.1* | 1.4 | 1.0–2.0 | 1.9 |
Corticosterone | 8.2*# | 3.0–17.8 | 4.8*# | 18.4* +  | 10.3–25.2 | 7.8 +  | 30.3 | 27.4–34.4 | 14.3 |
Cortisol | 328.2* | 222.3–472.9 | 1.5 | 352.1* | 281.6–447.1 | 1.9 | 258.6 | 244.9–269.3 | 2.1 |
Cortisone | 16.9 | 15.1–21.3 | 1.2 | 17.6 | 13.7–22.2 | 1.1 | 19.5 | 17.6–20.5 | 1.0 |