Table 1 Risk factors, recorded during the index hospitalization, for 1-year hospital readmission for recurrent sepsis for 178,017 adult patients hospitalized with sepsis in metropolitan France in 2018: univariate and multivariate logistic regressions
cORa (99% CI) | P value | aORa (99% CI) | P value | |
|---|---|---|---|---|
Patient characteristics | ||||
Sex (ref = men) | 0.76 (0.73–0.78) | < 0.001 | 0.85 (0.82–0,89) | < 0.0001 |
Age (ref = 16–30) | < 0.001 | < 0.001 | ||
31–45 | 1.37 (1.19–1.58) | 1.21 (1.04–1.39) | ||
46–55 | 1.80 (1.58–2.06) | 1.35 (1.18–1.54) | ||
56–65 | 2.17 (1.92–2.46) | 1.51 (1.33–1.72) | ||
66–75 | 2.28 (2.01–2.57) | 1.57 (1.38–1.78) | ||
76–85 | 1.87 (1.66–2.12) | 1.40 (1.23–1.59) | ||
> 85 | 1.37 (1.20–1.55) | 1.14 (1.00–1.31) | ||
Heart failure (ref = no) | 1.09 (1.04–1.14) | < 0.001 | 1.14 (1.09–1.19) | < 0.001 |
Dementia (ref = no) | 0.68 (0.62–0.75) | < 0.001 | 0.82 (0.74–0.90) | < 0.001 |
Chronic pulmonary disease (ref = no) | 1.08 (1.02–1.14) | < 0.001 | 1.08 (1.02–1.14) | 0,001 |
Rheumatologic disease (ref = no) | 1.21 (1.04–1.41) | 0.001 | 1.33 (1.14–1.55) | < 0.001 |
Liver disease (ref = no) | 1.45 (1.35–1.56) | < 0.001 | 1.33 (1.23–1.43) | < 0.001 |
Diabetes with chronic complications (ref = no) | 1.49 (1.39–1.59) | < 0.001 | 1.29 (1.20–1.39) | < 0.001 |
Paraplegia and hemiplegiab (ref = no) | 1.00 (0.92–1.08) | 0.901 | – | |
Renal disease (ref = no) | 1.54 (1.47–1.62) | < 0.001 | 1.55 (1.47–1.63) | < 0.001 |
Cancer (ref = no) | 2.14 (2.06–2.23) | < 0.001 | 1.98 (1.90–2.07) | < 0.001 |
AIDS HIV (ref = no) | 1.36 (1.06–1.74) | 0.001 | 1.30 (1.01–1.67) | 0.008 |
Hospital stay characteristics | ||||
Hospital discharge (ref = Home) | < 0.001 | < 0.001 | ||
Acute care | 1.02 (0.97–1.07) | 1.04 (0.99–1.10) | ||
Home care | 1.47 (1.28–1.70) | 1.06 (0.92–1.23) | ||
Long-term care | 0.91 (0.86–0.95) | 0.86 (0.82–0.91) | ||
Length of stay (in days) (ref ≤ 7) | < 0.001 | < 0.001 | ||
7–30 | 1.26 (1.19–1.34) | 1.16 (1.09–1.23) | ||
31–90 | 1.71 (1.60–1.83) | 1.48 (1.37–1.59) | ||
> 90 | 2.11 (1.84–2.42) | 1.98 (1.71–2.29) | ||
ICU admission and septic shock (ref = absence of both) | < 0.001 < 0.001 | |||
No ICU admission and septic shock | 0.82 (0.71–0.96) | 0.91 (0.78–1.06) | ||
ICU admission and septic shock | 1.07 (1.01–1.12) | 0.97 (0.92–1.03) | ||
ICU admission and no septic shock | 0.87 (0.84–0.91) | 0.82 (0.79–0.86) | ||
Infection characteristics | ||||
Site (ref = Urinary and genital tracts) | < 0.001 | < 0.001 | ||
Gastrointestinal and abdomen | 1.25 (1.15–1.36) | 1.16 (1.06–1.26) | ||
Primary bacteraemia | 1.49 (1.40–1.58) | 1.28 (1.20–1.36) | ||
Bones and joints | 1.14 (0.99–1.30) | (0.94–1.24) | ||
Heart and mediastinum | 1.92 (1.76–2.09) | 1.47 (1.35–1.61) | ||
Multiple | 1.33 (1.25–1.41) | 1.09 (1.03–1.17) | ||
Material device | 1.35 (1.22–1.49) | 1.06 (0.96–1.17) | ||
Lower respiratory tract | 0.94 (0.89–1.01) | 0.92 (0.86–0.99) | ||
Skin and soft tissues | 1.37 (1.25–1.50) | 1.23 (1.12–1.35) | ||
Others | 0.47 (0.40–0.55) | 0.54 (0.46–0.64) | ||