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Fig. 3 | Critical Care

Fig. 3

From: An area under the concentration–time curve threshold as a predictor of efficacy and nephrotoxicity for individualizing polymyxin B dosing in patients with carbapenem-resistant gram-negative bacteria

Fig. 3

Scatterplot of polymyxin B AUCss,24 h and C0h stratified for outcomes. AUCss,24 h for AKI (a), clinical efficacy (b), and survival (c); C0h for AKI (d), clinical efficacy (e), and survival (f). AUCss,24 h, the area under the plasma concentration–time curve across 24 h at steady state; C0h, trough concentration; AKI, acute kidney injury; ***represent P < 0.001; and *represent P < 0.05

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Critical Care

ISSN: 1364-8535