Hospital change to mixed lipid emulsion from soybean oil-based lipid emulsion for parenteral nutrition in hospitalized and critically ill adults improves outcomes: a pre–post-comparative study

Table 6 Associations of 4-OLE with outcomes among adults in intensive care unit

	Intralipid^*	4-OLE	Unadjusted analysis	Adjusted analysis	p-value
	(N = 110)	(N = 337)	p value	IRR (95% CI)	p-value
LOS, median (IQR)	32.7 (22.2–46.2)	27.8 (16.4–45.7)	0.013	0.91 (0.87, 0.94)	< 0.0001
ICU LOS, median (IQR)	3.5 (1.0–6.0)	2.0 (1.0–6.0)	0.08	0.90 (0.82, 0.99)	0.036

	Intralipid^*	4-OLE	Unadjusted analysis	Adjusted analysis	p-value
	(N = 110) (%)	(N = 337) (%)	p value	OR (95% CI)	p-value
Hospital mortality	22 (20.0)	75 (22.3)	0.62	1.17 (0.66, 2.06)	0.6
30 day readmission	30 (27.3)	65 (19.3)	0.08	0.61 (0.36, 1.04)	0.067
90 day readmission	63 (57.3)	185 (54.9)	0.66	0.88 (0.55, 1.39)	0.58
Any infection	66 (60.0)	197 (58.5)	0.78	0.90 (0.56, 1.43)	0.65
Pneumonia	22 (20.0)	75 (22.3	0.62	1.13 (0.64, 2.00)	0.66
UTI	19 (17.3)	33 (9.8)	0.034	0.50 (0.26, 0.96)	0.038

We adjusted for age, sex, race, ethnicity, insurance status, cancer, malnutrition, ED admission, and BMI in kg/m²
LOS Length of stay, ICU Intensive care unit, IRR Incident rate ratio, OR Odds ratio, UTI Urinary tract infection, CI Confidence interval; and 4-OLE SMOFLipid
^*Intralipid—(Baxter Inc, Deerfield, IL, USA)

ISSN: 1364-8535