Table 5 Unadjusted and adjusted analysis for nutrition profiles and liver function tests among adults in intensive care unit
Intralipid* | 4-OLE | Unadjusted analysis | Adjusted analysis | p-value | |
|---|---|---|---|---|---|
(N = 110) | (N = 337) | p value | Estimate (95% CI) | ||
Total days receiving lipids, median (IQR) | 10.0 (6.0–15.0) | 9.0 (5.0–19.0) | 0.91 | 2.05 (− 0.64, 4.73) | 0.13 |
Daily lipid dosage (g/kg/day), median (IQR) | 0.5 (0.4–0.7) | 0.6 (0.4–0.7) | 0.08 | 0.06 (0.01, 0.11) | 0.018 |
Daily calories (calories/kg/day), median (IQR) | 21.5 (17.2–27.7) | 23.1 (18.7–29.6) | 0.08 | 0.26 (− 0.06, 0.59) | 0.11 |
Daily protein (g/kg/day), median (IQR) | 0.8 (0.7–0.9) | 0.8 (0.7–1.0) | 0.041 | 0.03 (− 0.01, 0.08) | 0.11 |
Daily dextrose (g/kg/day), median (IQR) | 1.4 (1.0–1.8) | 1.4 (1.0–1.9) | 0.44 | 0.05 (− 0.07, 0.16) | 0.46 |
Liver function tests, median (IQR) | |||||
Delta AST (units/L) | 27.0 (8.0–99.0) | 27.5 (8.0–99.0) | 0.85 | 45.3 (− 201.1, 291.8) | 0.72 |
Delta ALT (units/L) | 26.0 (4.0–78.0) | 24.0 (5.0–97.0) | 0.79 | 41.7 (− 60.4, 143.7) | 0.42 |
Delta ALP (international units/L) | 56.0 (17.0–153.0) | 47.0 (10.0–160.0) | 0.78 | 11.6 (− 28.5, 51.7) | 0.57 |
Delta total bilirubin (mg/dL) | 1.1 (0.5–3.2) | 1.0 (0.4–2.5) | 0.28 | − 1.6 (− 2.9, − 0.2) | 0.021 |