Table 2 Unadjusted and adjusted analysis for nutrition profiles and liver function tests among all adults
Intralipid* | 4-OLE | Unadjusted analysis | Adjusted analysis | ||
|---|---|---|---|---|---|
(N = 341) | (N = 859) | p value | Estimate (95% CI) | p-value | |
Total days receiving lipids, median (IQR) | 8.0 (4.0–12.5) | 7.0 (3.0–15.0) | 0.62 | 1.49 (0.11, 2.87) | 0.034 |
Daily lipid dosage (g/kg/day), median (IQR) | 0.6 (0.4–0.7) | 0.6 (0.4–0.8) | 0.041 | 0.03 (− 0.01, 0.06) | 0.11 |
Daily calories (calories/kg/day), median (IQR) | 23.7 (18.8–28.9) | 24.8 (19.3–30.6) | 0.1 | 0.18 (− 0.02, 0.37) | 0.076 |
Daily protein (g/kg/day), median (IQR) | 0.8 (0.7–1.0) | 0.9 (0.7–1.0) | 0.06 | 0.02 (− 0.00, 0.05) | 0.0763 |
Daily dextrose (g/kg/day), median (IQR) | 1.5 (1.1–1.9) | 1.5 (1.1–2.0) | 0.45 | 0.04 (− 0.04, 0.11) | 0.3104 |
Liver function tests, median (IQR) | |||||
Delta AST (units/L) | 15.0 (2.0–42.0) | 16.0 (2.0–52.5) | 0.4 | 61.9 (− 62.1, 185.8) | 0.33 |
Delta ALT (units/L) | 13.0 (0.5–44.5) | 16.0 (1.0–54.5) | 0.23 | 44.9 (− 8.6, 98.4) | 0.1 |
Delta ALP (international units/L) | 27.0 (3.0–63.0) | 26.5 (0.0–104.0) | 0.25 | 29.0 (6.2, 51.8) | 0.013 |
Delta total bilirubin (mg/dL) | 0.5 (0.2–1.3) | 0.6 (0.1–1.4) | 0.85 | − 0.4 (− 1.0, 0.2) | 0.21 |