Skip to main content

Table 2 Characteristics of study patients by day 0 N-formylmethionine abundance quartiles

From: Circulating N-formylmethionine and metabolic shift in critical illness: a multicohort metabolomics study

Characteristics

N-formylmethionine abundance at day 0

P value

Q1

Q2

Q3

Q4

VITdAL-ICU cohort

No

107

107

107

107

 

Age mean (SD)

56.3 (15.3)

62.1 (17.0)

68.1 (11.7)

70.2 (10.7)

 < 0.001*

Female sex no. (%)

41 (38)

32 (30)

39 (36)

39 (36)

0.59

Non-White no. (%)

0 (0)

0 (0)

0 (0)

0 (0)

 

SAPS II mean (SD)

32.5 (17.0)

32.7 (16.2)

33.7 (13.4)

34.5 (15.0)

0.76*

Sepsis no. (%)

2 (2)

9 (8)

7 (7)

13 (12)

0.033

Creatinine day 0 mean (SD)

0.91 (0.62)

1.05 (0.55)

1.50 (0.86)

2.15 (1.28)

 < 0.001*

Procalcitonin ng/ml day 0 median [IQR]

0.14 [0.06, 0.45]

0.20 [0.08, 0.64]

0.62 [0.20, 1.94]

1.24 [0.45, 4.12]

0.001†

Propofol no. (%)

27 (25)

28 (26)

25 (27)

24 (23)

0.94

ICU

    

 < 0.009

 Anesthesia ICU no. (%)

24 (23)

16 (15)

20 (18)

22 (21)

 

 Cardiac surgery ICU no. (%)

19 (18)

32 (30)

41 (38)

34 (31)

 

 Surgical ICU No. (%)

4 (4)

6 (6)

6 (6)

6 (6)

 

 Medicine ICU no. (%)

19 (18)

22 (21)

20 (18)

30 (28)

 

 Neurological ICU no. (%)

40 (38)

31 (29)

21 (19)

15 (14)

 

28-Day mortality

13 (12)

16 (15)

25 (23)

41 (38)

 < 0.001

180-day mortality

24 (22)

25 (23)

43 (40)

63 (59)

 < 0.001

RoCI cohort

     

No

23

22

23

22

 

Age mean (SD)

48.5 (16.7)

59.6 (13.0)

56.5 (12.3)

55.5 (14.2)

0.06*

Female sex no. (%)

9 (39)

8 (36)

10 (43)

12 (55)

0.63

Non-White no. (%)

5 (22)

6 (27)

5 (22)

4 (18)

0.54

APACHE II mean (SD)

21.6 (11.6)

25.1 (9.5)

26.0 (9.4)

30.5 (6.8)

0.02*

Sepsis no. (%)

8 (38)

11 (55)

16 (73)

16 (89)

0.007

Creatinine day 0 mean (SD)

0.9 (0.5)

1.2 (0.6)

1.5 (1.0)

2.6 (1.9)

 < 0.001*

Procalcitonin ng/ml day 0 median [IQR]††

0.21 [0.91, 1.17]

0.48 [0.12, 2.50]

0.70 [0.22, 1.08]

1.08 [0.12, 8.73]

0.46†

ICU

     

 Medicine ICU no. (%)

23 (100)

22 (100)

23 (100)

22 (100)

 

28-Day mortality

5 (22)

7 (32)

6 (26)

12 (55)

0.093

180-Day mortality

8 (35)

9 (41)

9 (39)

13 (59)

0.37

  1. Data presented as n (%) unless otherwise indicated
  2. P values determined by chi-square unless designated by (*) then P value determined by ANOVA or by (†) determined by Kruskal-Wallis test. ††Procalcitonin measured in 53 of the RoCI cohort patients
Back to article page

Critical Care

ISSN: 1364-8535