Table 2 Fibrinolytic antigens levels. Fibrinogen, α₂AP, TAFI, PAI-1, tPA, FXIII and thrombomodulin (TM) antigen concentration were measured in plasma samples pre- and post-cryoprecipitate (cryo) and fibrinogen concentrate (Fg-C) transfusion. Grey dotted lines indicate the mean value for 16 healthy volunteers. *p < 0.05, **p < 0.01

Fibrinogen (mg/ml)

3.5 ± 3.2

1.6 ± 0.6

2.3 ± 1.1

ns

1.9 ± 0.5

2.5 ± 0.8

ns

α₂AP (µg/ml)

69.6 ± 27.2

33.6 ± 11

31.6 ± 12.2

ns

37 ± 10.4

31.6 ± 10.4

ns

TAFI (µg/ml)

8.1 ± 2

5.6 ± 2.4

5.3 ± 2.1

ns

5.5 ± 1.7

4.5 ± 1.8

*

PAI-1 (ng/ml)

11.7 ± 7.8

133.1 ± 159.7

278.3 ± 225.8

*

88.7 ± 81.9

93.7 ± 93.3

ns

tPA (ng/ml)

1.1 ± 0.5

3.5 ± 2.6

2.4 ± 1.3

ns

3.5 ± 1.7

3.8 ± 3

ns

FXIII (µg/ml)

39 ± 19.5

17.5 ± 3.8

22.5 ± 6.9

*

22.2 ± 7.2

18.3 ± 6.2

*

TM (ng/ml)

7.3 ± 1.7

9 ± 1.9

8.1 ± 2.3

ns

10.1 ± 6

9.6 ± 5.3

ns