Total (n = 75) | PEEPlower (n = 23) | PEEPequal (n = 28) | PEEPhigher (n = 24) | p value | |
---|---|---|---|---|---|
Male gender | 59 (79%) | 19 (83%) | 22 (79%) | 18 (75%) | 0.82 |
BMI (kg/m2) | 30.4 (5.8) | 27.8 (5.6) | 31.4 (5.5) | 31.6 (5.8) | 0.037* |
Age (y) | 64 [54–71] | 66 [60–73] | 64 [54–68] | 59 [53–70] | 0.27 |
Apache IV score at ICU admission | 70 (27) | 85 (32) | 66 (24) | 61 (19) | 0.004* |
Time since onset symptoms (d) | 14 [10–17] | 15 [14–26] | 14 [8–17] | 12 [7–16] | 0.061 |
Time since intubation (d) | 3 [1–8] | 4 [2–14] | 3 [2–6] | 2 [1–7] | 0.52 |
Time between onset symptoms and intubation (d) | 10 [7–12] | 10 [9–13] | 7 [6–12] | 8 [6–10] | 0.046* |
Time ventilated in other hospital (d) | 1 [0–4] | 2 [0–6] | 1 [0–3] | 1 [0–3] | 0.51 |
28-day mortality | 22 (29%) | 8 (35%) | 7 (25%) | 7 (29%) | 0.75 |
D-dimer at admission (mg/L) | 1.6 [0.9–3.5] | 2.9 [1.5–8.8] | 1.2 [0.7–2.8] | 1.3 [1.0–2.2] | 0.026* |
Pulmonary embolism at PEEP trial | 13 (17%) | 6 (26%) | 3 (11%) | 4 (17%) | 0.35 |
Proven pulmonary embolism during ICU admission | 38 (51%) | 17 (74%) | 12 (43%) | 9 (38%) | 0.026* |