Fig. 4

Molecular pathophysiological comparison of high-mortality phenotypes and other phenotypes. a Serum proteins differentially expressed between the high-mortality phenotype and other phenotypes (volcano plot). Red indicates proteins with upregulated expression, and blue indicates proteins with downregulated expression. The names of proteins demonstrating significantly different levels of expression are shown (false discovery rate < 0.2), as are those with fold changes >|1.2|. b Gene Ontology enrichment analysis identified 256 reliable proteins. Dots represent the top 12 enriched biological process terms. The color of the dots indicates significance (Benjamini–Hochberg adjusted p value), and their size indicates the number of differentially expressed proteins in the list of significant proteins associated with the GO term