Fig. 1From: The impact of extracorporeal membrane oxygenation on the exposure to isavuconazole: a plea for thorough pharmacokinetic evaluationTreatment course of cases A, B, C and D. Grey shaded area: extracorporeal membrane oxygenation support; points: isavuconazole trough concentrations (mg/L); black short lines: isavuconazole daily doses (mg); black dashed horizontal line: minimal isavuconazole trough concentration threshold of 1Â mg/L, based on the European Committee on Antimicrobial Susceptibility Testing breakpoints for Aspergillus fumigatus, A. flavus and A. terreus; grey dashed vertical line: lung transplantation. Cmin: trough concentration; Tx: transplantationBack to article page