Paradoxical response to chest wall loading predicts a favorable mechanical response to reduction in tidal volume or PEEP

Table 2 Ventilator settings and gas exchange at baseline

Subject	Pa_O2/Fi_O2	Pa_CO2 (mmHg)	V_T (mL/kg PBW)	PEEP set (cmH₂O)	RR	Ventilatory ratio
1	85	50.8	7	16	22	2.1
2	137.5	101	4.9	12	30	4.0
3	109.3	66.7	6	7.5	24	2.6
4	83	81.3	5.4	6	32	3.7
5	87	62.6	3.9	6	27	1.8
6	157.2	65.3	5.9	9	32	3.3
7	245	63.4	5.5	12	22	2.0
8	82.2	63.2	5.9	5	30	3.0
9	86.9	61.5	5.4	8	32	2.8
10	147	48.1	7	14	34	3.1
11	191.4	47.4	5.9	12	28	2.1
12	160	74.3	6.6	10	24	3.1
13	98.3	49	4.6	10	32	1.9
14	102.5	45	5.2	8	28	1.7
15	65.6	59	4.6	12	34	2.5
16	185.5	58.7	6.7	12	26	2.7
17	73.4	92.7	4.7	6	34	4.0
Mean	123.3	64.1	5.6	9.7	28.9	2.7
SD	50.7	15.7	0.9	3.2	4.2	0.7

Pa_O2 Partial pressure of arterial oxygen, Fi_O2 Fraction of inspired oxygen, Pa_CO2 Partial pressure of arterial carbon dioxide, V_T Tidal volume, PEEP Positive end-expiratory pressure, RR Respiratory rate, SD Standard deviation. Ventilatory ratio is defined as [minute ventilation (mL/min) x Pa_CO2 (mmHg)]/(predicted body weight × 100 × 37.5)

ISSN: 1364-8535