Skip to main content

Table 3 Haemodynamic parameters before and after fluid challenge administration in responders and non-responders

From: Fluid challenge in critically ill patients receiving haemodynamic monitoring: a systematic review and comparison of two decades

Haemodynamic variable

% DR

Pre FC

Post FC

% change pre versus post FC

p value–pre FC

R versus NR

p value

pre FC versus post FC

CI (L/min/m2)

44.3

     

 R

 

2.8 (2.5–3.2)

3.6 (3.0–4.1)

29 (23–33)

0.0003

< 0.0001

 NR

 

3.3 (2.7–3.6)

3.4 (2.9–3.7)

5 (0–6)

 

0.09

SVI (ml/m2)

22.6

     

 R

 

29 (26–33)

39 (36–42)

29 (25–38)

0.0001

< 0.0001

 NR

 

36 (31–41)

37 (31–42)

3 (− 1; 7)

 

0.05

MAP (mmHg)

73.4

     

 R

 

70 (68–74)

82 (77–85)

14 (10–18)

0.005

< 0.0001

 NR

 

74 (70–80)

78 (75–85)

6 (4–8)

 

< 0.0001

SAP (mmHg)

33.9

     

 R

 

104 (99–108)

123 (113–129)

17 (12–22)

0.002

< 0.0001

 NR

 

109 (105–118)

116 (109–123)

5 (4–8)

 

< 0.0001

PAOP (mmHg)

14.5

     

 R

 

11 (10–12)

15 (12–16)

28 (18–45)

0.05

< 0.0001

 NR

 

13 (10–14)

16 (13–18)

28 (15–37)

 

0.005

CVP (mmHg)

42.7

     

 R

 

9 (7–11)

11 (10–13)

30 (19–41)

0.03

< 0.0001

 NR

 

10 (8–12)

13 (10–15)

26 (15–38)

 

< 0.0001

HR (beats/min)

75.8

     

 R

 

98 (88–105)

94 (86–101)

− 3 (− 4; − 1)

0.03

< 0.0001

 NR

 

94 (86–101)

91 (84–98)

− 2 (− 3; − 1)

 

< 0.0001

PPV (%)

30.6

     

 R

 

15 (12–18)

9 (5–11)

− 42 (− 53; − 29)

< 0.0001

< 0.0001

 NR

 

8 (6–10)

7 (5–9)

− 15 (− 28; 0)

 

0.0002

SVV (%)

14.5

     

 R

 

14 (12–17)

10 (6–12)

− 36 (− 45; − 30)

< 0.0001

0.0002

 NR

 

11 (8–13)

9 (6–11)

− 22 (− 33; − 9)

 

0.002

  1. Data are presented as median (25th–75th interquartile) in responders (R) and non-responders (NR), n = 21; FC, fluid challenge; CI, cardiac index; SVI, stroke volume index; MAP, mean arterial pressure; SAP, systolic pressure variation; HR, heart rate; PPV, pulse pressure variation; SVV, stroke volume variation, CVP, central venous pressure; PAOP, pulmonary artery occluded pressure; %DR, percentage of data reported in the studies