Intermediate-risk pulmonary embolism: echocardiography predictors of clinical deterioration

Table 4 Final logistic model for 5-day clinical deterioration

	Clinical Deterioration within 5 days
Predictors	Odds ratios	Confidence interval	p value
Initial BNP level (per 100 pg/mL)	1.10	1.03–1.19	0.008
Tricuspid regurg peak velocity, m/s	0.77	0.58–1.01	0.071
RV/LV basal width ratio (per 10% point increase in ratio)	1.29	1.14–1.47	< 0.001
Age	0.97	0.96–0.99	0.010
Highest heart rate (within 3 h)*	1.02	1.00–1.03	0.039
Highest respiratory rate (within 3 h)**	1.02	1.00–1.04	0.109
Lowest O₂ saturation within 3 h***	0.94	0.89–0.99	0.033
SBP < 90 mmHg for < 15 min prior to enrollment?	6.18	2.24–18.92	0.001
Indwelling vascular catheter? (e.g., portacath)	0.19	0.03–0.81	0.047
Congestive heart failure	2.83	0.82–9.51	0.095
Anticoagulant initiated in ED?	0.08	0.00–0.54	0.029
Observations	331
R2 Tjur	0.318

Abbreviations: BNP brain natriuretic peptide, RV/LV right ventricle-to-left ventricle ratio, SBP systolic blood pressure, ED emergency department
^*For each additional maximum heart rate in beats per minute or **respiratory rate in breaths per minute within the first 3 h, the ORs were 1.02, i.e., their odds of clinical deterioration increased by 2%
^***For initial O2 sat, we see an OR of 0.94 or every percentage point decrease in max O2 within 3 h, a patient's odds of clinical deterioration increased by 6%

ISSN: 1364-8535