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Table 2 Effects of prone position ventilation on respiratory, gas exchange, and hemodynamics

From: Prone positioning improves ventilation–perfusion matching assessed by electrical impedance tomography in patients with ARDS: a prospective physiological study

 

T0

T1

T2

Trend-P value

Mauchly’s test of sphericity P value

MV (l/min)

7.47 ± 1.09

7.29 ± 0.92

7.62 ± 1.32

0.536

< 0.001

Crs (ml/cmH2O)

27.70 ± 11.65

30.03 ± 11.36

33.52 ± 12.87a

< 0.01

0.061

Set FiO2

0.70 [0.60–0.89]

0.60 [0.59–0.69]

0.60 [0.40–0.65]

< 0.05

0.441

PaO2 (mmHg)

66.98 ± 12.15

100.44 ± 20.54a

125.35 ± 34.85a

< 0.0001

0.119

PaO2/FiO2 (mmHg)

95.40 ± 27.45

161.90 ± 44.68a

221.40 ± 54.64a, b

< 0.0001

0.957

PaCO2 (mmHg)

50.55 [41.50–63.35]

56.45 [46.33–69.93]

49.90 [42.88–68.58]

0.257

0.046

ETCO2 (mmHg)

36.00 [34.00–48.75]

41.00 [35.00–50.00]

37.50 [33.00–43.25]

0.348

0.010

Dead space-ABG

26.84 [17.66–34.42]

24.56 [21.64–33.43]

20.02 [17.61–37.17]

0.740

0.003

HR (bpm)

113.30 ± 19.81

108.00 ± 20.56

106.90 ± 24.53

0.387

0.198

SBP (mmHg)

116.20 ± 17.50

120.50 ± 17.80

121.60 ± 19.00

0.763

0.070

MAP (mmHg)

76.93 ± 15.97

84.83 ± 13.77

84.60 ± 17.33

0.360

0.092

CVP (mmHg)

10.00 [8.00–14.50]

14.00 [10.50–15.00]

13.00 [11.00–15.00]

0.123

0.253

Norepinephrine (µg/kg/min)

0.17 [0–0.175]

0.08 [0–0.175]

0.02 [0–0.088]a

< 0.05

0.377

  1. MV, minute ventilation; PaO2/FiO2, arterial partial pressure of O2/inspired fraction of O2 ratio; PaCO2, arterial partial pressure of CO2; ETCO2, end-tidal expired carbon dioxide pressure; ABG, arterial blood gas; HR, heart rate; SBP, systolic arterial blood pressure; MAP, mean arterial pressure; CVP, central venous pressure. Respiratory system static compliance (Crs) = Vt/(Pplat − PEEPtot) from the analysis of ventilation tracings during occlusions; Vt, tidal volume; Pplat, plateau pressure; PEEPtot, total positive end-expiratory pressure. T0: in the supine position; T1: 3 h after PP initiation; T2: at the end of PP
  2. p value by one-way analysis of variance (ANOVA) for repeated measures
  3. avs. T0p < 0.05
  4. bvs. T1p < 0.05