Cardiopulmonary resuscitation duration and favorable neurological outcome after out-of-hospital cardiac arrest: a nationwide multicenter observational study in Japan (the JAAM-OHCA registry)

Table 2 Outcomes from OHCA according to CPR duration

	Total	Outcome (%)	Crude OR	(95% CI)	Adjusted OR	(95% CI)
1-month survival
≤ 20 min	1084	349 (32.2)	Reference		Reference*
21–30 min	3165	190 (6.0)	0.14	(0.11–0.16)	0.25	(0.20–0.31)
31–40 min	5466	93 (1.7)	0.04	(0.03–0.05)	0.08	(0.06–0.10)
41–60 min	9378	46 (0.5)	0.01	(0.01–0.01)	0.02	(0.013–0.026)
61–90 min	3990	8 (0.2)	0.004	(0.002–0.009)	0.005	(0.003–0.011)
91–120 min	708	1 (0.1)	0.003	(0.000–0.021)	0.003	(0.000–0.023)
P for trend^†				< 0.001		< 0.001
Favorable neurological outcome
≤ 20 min	1084	226 (20.8)	Reference		Reference*
21–30 min	3165	37 (1.2)	0.05	(0.03–0.06)	0.15	(0.10–0.23)
31–40 min	5466	24 (0.4)	0.02	(0.011–0.03)	0.08	(0.05–0.12)
41–60 min	9378	12 (0.1)	0.005	(0.003–0.009)	0.02	(0.01–0.031)
61–90 min	3990	2 (0.1)	0.002	(0.000–0.008)	0.004	(0.001–0.016)
91–120 min	708	0 (0.0)	NA		NA
P for trend^†				< 0.001		< 0.001

OHCA indicates out-of-hospital cardiac arrest; OR, odds ratio; and CI, confidence interval
*Adjusted for age, sex, cardiac etiology of arrest, bystander witness, bystander CPR, first documented rhythm at the scene, prehospital advanced airway management, prehospital adrenaline administration, EMS response time
^†CPR duration treated as continuous variable

ISSN: 1364-8535