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Table 4 Multivariable linear regressions of serum IL-17 as the independent variable and secondary outcomes as dependent variables

From: Serum IL-17 levels are higher in critically ill patients with AKI and associated with worse outcomes

Biomarker

Outcome

β (95% CI)

p value

Interaction p value#

IL-17A * AKI status

Serum IL-17, per onefold increase

Days in the hospital

0.08 (0.03–0.14)

0.005

0.006

 

Days in the ICU

0.07 (0.01–0.14)

0.045

0.108

 

Days on mechanical ventilation

0.19 (0.05–0.32)

0.008

0.130

  1. All models were adjusted for age, gender, race, Charlson comorbidity index, baseline eGFR, non-renal APACHE II, study site, and serum creatinine at the time of sample collection (t1)
  2. ICU intensive care unit
  3. #Interaction p value denotes the statistical interaction between IL-17A and AKI status (AKI vs. non-AKI) for the secondary study outcomes
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Critical Care

ISSN: 1364-8535