Table 1 Baseline ICU and Patient-Level Characteristics
Characteristics | Feeding guideline 48 ICUs, 1399 pts | Control 49 ICU, 1373 pts | P value |
|---|---|---|---|
ICU-level characteristics | |||
Tertiary, No. (%) | 34 (70.8) | 37 (75.5) | 0.61 |
ICU type, No. (%) | Â | Â | 0.97 |
Emergency | 2 (4.2) | 2 (4.1) | Â |
Medical | 1 (2.1) | 1 (2) | Â |
Neuro | 1 (2.1) | 1 (2) | Â |
Surgical | 2 (4.2) | 2 (4.1) | Â |
General | 42 (87.5) | 43 (87.8) | Â |
Patient-level characteristics | Â | Â | Â |
Age, mean ± SD, y | 61.0 ± 17.6 | 60.1 ± 17.7 | 0.98 |
Male, No. (%) | 938 (67.0%) | 928 (67.6%) | 0.56 |
BMI, mean ± SD, kg/m2 | 22.8 ± 3.2 | 23.1 ± 3.2 | 0.27 |
APACHE II score, mean ± SD | 18.3 ± 6.8 | 18.6 ± 7.6 | 0.63 |
mNUTRIC score, mean ± SD | 4.28 ± 1.96 | 4.30 ± 2.05 | 0.97 |
SOFA score, mean ± SD | 7.5 ± 3.4 | 8.1 ± 3.7 | 0.07 |
Proportion of organ failure (SOFA score for individual system ≥ 2), No. (%) |  |  |  |
Respiration | 968 (72.1%) | 1043 (78.4%) | 0.10 |
Renal | 284 (21.2%) | 316 (23.7%) | 0.46 |
Cardiovascular | 384 (28.6%) | 450 (33.8%) | 0.52 |
Proportion of patients receiving organ support, No. (%) | Â | Â | Â |
Mechanical ventilation | 921 (68.6%) | 966 (72.5%) | 0.242 |
Renal replacement therapy | 127 (9.5%) | 204 (15.3%) | 0.018 |
Vasoactive drugs | 401 (29.9%) | 523 (39.3%) | 0.051 |
Gastrointestinal function, No. (%) | Â | Â | 0.09 |
AGI-I | 1019 (75.9%) | 888 (66.5%) | Â |
AGI-II | 236 (17.6%) | 290 (21.7%) | Â |
AGI-III | 50 (3.7%) | 126 (9.4%) | Â |
AGI-IV | 37 (2.8%) | 31 (2.3%) | Â |
Comorbidities, No. (%) | Â | Â | Â |
Hypertension | 617 (44.1%) | 574 (41.8%) | 0.36 |
Coronary disease | 214 (15.3%) | 250 (18.2%) | 0.31 |
Diabetes | 236 (16.9%) | 265 (19.3%) | 0.20 |
Chronic Respiratory diseases | 146 (10.4%) | 122 (8.9%) | 0.31 |
Stroke | 211 (15.1%) | 175 (12.7%) | 0.42 |
Gastrointestinal disease | 76 (5.4%) | 125 (9.1%) | 0.13 |
Malignant tumor | 43 (3.1%) | 59 (4.3%) | 0.44 |
Others | 524 (37.5%) | 497 (36.2%) | 0.84 |