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Table 3 Correlation between regional CBF and monitoring parameters. The discriminative ability of each variable or combination to predict cerebral hypoperfusion (i.e., regional CBF < 35 mL/100 g × min) was evaluated using receiver operating characteristic curves with the corresponding area under the curve (AUROC), and sensitivity, specificity, positive (PPV) and negative predictive value (NPV) were computed

From: Detection of cerebral hypoperfusion with a dynamic hyperoxia test using brain oxygenation pressure monitoring

 

Correlation with rCBF

AUROC (95% CI)

ICP

r = − 0.27; p = 0.01

0.65 (0.53–0.76)

PbtO2

r = 0.36; p < 0.01

0.75 (0.64–0.85)

Oxygen ratio

r = 0.57; p < 0.01

0.75 (0.63–0.85)

CPP

r = 0.01; p = 0.92

0.57 (0.44–0.70)

ICP + PbtO2

–

0.78 (0.68–0.87)

ICP + OxR

–

0.78 (0.68–0.88)

ICP + PbO2 + oxygen ratio

–

0.80 (0.70–0.91)

  1. ICP intracranial pressure, CPP cerebral perfusion pressure, PbtO2 brain tissue oxygen pressure, CI confidence intervals