Table 2 Differences in main available data on the day of cerebral CT perfusion (CTP), according to the presence of brain hypoperfusion (i.e., regional cerebral blood flow < 35 mL/100 g × min). Data are presented as count (%) or median [IQRs]
|  | ALL (n = 87) | Brain hypoperfusion (n = 56) | No brain hypoperfusion (n = 31) | p value |
|---|---|---|---|---|
Baseline | ||||
ICP, mmHg | 13 [9–17] | 15 [9–19] | 11 [8–15] | 0.02 |
CPP, mmHg | 94 [80–110] | 95 [81–112] | 86 [79–108] | 0.36 |
PbtO2, mmHg | 21 [19–23] | 20 [18–22] | 22 [21–25] | < 0.01 |
PaO2, mmHg | 110 [98–124] | 112 [97–127] | 109 [99–122] | 0.79 |
FiO2 at baseline, % | 35 [30–40] | 35 [30–40] | 30 [30–40] | 0.04 |
PaO2/FiO2 at baseline | 327 [283–365] | 312 [269–357] | 338 [297–370] | 0.10 |
PEEP, cmH2O | 8 [5–10] | 8 [5–10] | 8 [5–10] | 0.68 |
pH | 7.42 [7.38–7.44] | 7.42 [7.38–7.44] | 7.41 [7.39–7.43] | 0.82 |
PaCO2 baseline, mmHg | 39 [36–43] | 39 [37–42] | 38 [35–41] | 0.06 |
Sodium, mmol/L | 140 [138–144] | 140 [138–144] | 140 [138–142] | 0.59 |
Hemoglobin, g/dL | 10.3 [9.1–11.4] | 10.2 [9.6–11.6] | 10.5 [8.9–11.3] | 0.56 |
Glucose, mg/dL | 134 [121–145] | 133 [119–144] | 138 [126–154] | 0.20 |
Body temperature, °C | 37.1 [36.8–37.5] | 37.2 [36.7–37.6] | 37.1 [36.9–37.5] | 0.98 |
Sedatives, n (%) | 48 (55) | 31 (55) | 17 (55) | 1.00 |
Opioids, n (%) | 54 (62) | 34 (61) | 20 (65) | 0.82 |
NMBAs, n (%) | 22 (25) | 14 (25) | 8 (26) | 1.00 |
Norepinephrine, n (%) | 66 (76) | 43 (77) | 23 (74) | 0.80 |
Inotropic agents, n (%) | 20 (23) | 13 (23) | 7 (23) | 1.00 |
End of the dynamic oxygen challenge | ||||
PbtO2, mmHg | 79 [56–95] | 62 [46–88] | 91 [81–119] | < 0.01 |
PaO2, mmHg | 359 [319–410] | 345 [315–407] | 378 [339–418] | 0.08 |
pH | 7.42 [7.38–7.43] | 7.42 [7.37–7.44] | 7.42 [7.39–7.43] | 0.74 |
PaCO2, mmHg | 39 [36–44] | 39 [36–44] | 38 [36–42] | 0.72 |
Oxygen ratio | 0.23 [0.15–0.29] | 0.21 [0.12–0.27] | 0.28 [0.22–0.33] | < 0.01 |
rCBF, mL/100 g × min | 31.3 [22.6–41.3] | 25.6 [15.4–31.2] | 49.3 [40.4–68.0] | < 0.01 |